Chitinase 3-like-1 protects airway function despite promoting type 2 inflammation during fungal-associated allergic airway inflammation.
作者信息
Mackel Joseph J, Garth Jaleesa M, Jones MaryJane, Ellis Diandra A, Blackburn Jonathan P, Yu Zhihong, Matalon Sadis, Curtiss Miranda, Lund Frances E, Hastie Annette T, Meyers Deborah A, Steele Chad
机构信息
Department of Medicine, University of Alabama Birmingham, Birmingham, Alabama.
Department of Microbiology and Immunology, Tulane University, New Orleans, Louisiana.
出版信息
Am J Physiol Lung Cell Mol Physiol. 2021 Apr 1;320(4):L615-L626. doi: 10.1152/ajplung.00528.2020. Epub 2021 Feb 3.
Abstract
摘要
相似文献
1
Chitinase 3-like-1 protects airway function despite promoting type 2 inflammation during fungal-associated allergic airway inflammation.几丁质酶3样蛋白1在真菌相关的过敏性气道炎症中尽管会促进2型炎症反应，但仍能保护气道功能。
Am J Physiol Lung Cell Mol Physiol. 2021 Apr 1;320(4):L615-L626. doi: 10.1152/ajplung.00528.2020. Epub 2021 Feb 3.
2
Endogenous attenuation of allergic lung inflammation by syndecan-1.Syndecan-1对过敏性肺部炎症的内源性衰减作用
J Immunol. 2005 May 1;174(9):5758-65. doi: 10.4049/jimmunol.174.9.5758.
3
Aspergillus fumigatus proteases, Asp f 5 and Asp f 13, are essential for airway inflammation and remodelling in a murine inhalation model.烟曲霉蛋白酶，Asp f 5 和 Asp f 13，在小鼠吸入模型中对于气道炎症和重塑是必需的。
Clin Exp Allergy. 2015 May;45(5):982-993. doi: 10.1111/cea.12426.
4
CD48 is critically involved in allergic eosinophilic airway inflammation.CD48 在过敏性嗜酸性粒细胞性气道炎症中起关键作用。
Am J Respir Crit Care Med. 2007 May 1;175(9):911-8. doi: 10.1164/rccm.200605-695OC. Epub 2007 Feb 8.
5
A Toll-like receptor 2/6 agonist reduces allergic airway inflammation in chronic respiratory sensitisation to Timothy grass pollen antigens.TLR2/6 激动剂可减轻 Timothy 草花粉抗原慢性呼吸道致敏导致的过敏气道炎症。
Int Arch Allergy Immunol. 2010;152(2):131-9. doi: 10.1159/000265534. Epub 2009 Dec 16.
6
TLR9-IL-2 axis exacerbates allergic asthma by preventing IL-17A hyperproduction.Toll样受体9-白细胞介素-2轴通过阻止白细胞介素-17A过度产生而加重过敏性哮喘。
Sci Rep. 2020 Oct 22;10(1):18110. doi: 10.1038/s41598-020-75153-y.
7
Toll-like receptor 9 modulates immune responses to Aspergillus fumigatus conidia in immunodeficient and allergic mice.Toll样受体9调节免疫缺陷和过敏小鼠对烟曲霉分生孢子的免疫反应。
Infect Immun. 2009 Jan;77(1):108-19. doi: 10.1128/IAI.00998-08. Epub 2008 Oct 20.
8
Aryl hydrocarbon receptor deficiency enhanced airway inflammation and remodeling in a murine chronic asthma model.芳烃受体缺失增强了小鼠慢性哮喘模型中的气道炎症和重塑。
FASEB J. 2020 Nov;34(11):15300-15313. doi: 10.1096/fj.202001529R. Epub 2020 Sep 22.
9
Semaphorin 3E Inhibits House Dust Mite-Induced Angiogenesis in a Mouse Model of Allergic Asthma.信号素 3E 抑制变应性哮喘小鼠模型中屋尘螨诱导的血管生成。
Am J Pathol. 2019 Apr;189(4):762-772. doi: 10.1016/j.ajpath.2019.01.008. Epub 2019 Jan 31.
10
Androgen receptor activation alleviates airway hyperresponsiveness, inflammation, and remodeling in a murine model of asthma.雄激素受体激活可减轻哮喘小鼠模型的气道高反应性、炎症和重塑。
Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L803-L818. doi: 10.1152/ajplung.00441.2020. Epub 2021 Mar 10.
引用本文的文献
1
Fungal chitin is not an independent mediator of allergic fungal asthma severity.真菌几丁质不是变应性真菌性哮喘严重程度的独立介导物。
Am J Physiol Lung Cell Mol Physiol. 2024 Sep 1;327(3):L293-L303. doi: 10.1152/ajplung.00041.2024. Epub 2024 Jun 25.
2
Chitinase-3-like 1 regulates T2 cells, T cells and IgE responses to helminth infection.几丁质酶 3 样蛋白 1 调节 T2 细胞、T 细胞和 IgE 对寄生虫感染的反应。
Front Immunol. 2023 Jul 27;14:1158493. doi: 10.3389/fimmu.2023.1158493. eCollection 2023.
3
Hematopoietic 12/15-lipoxygenase activity negatively contributes to fungal-associated allergic asthma.造血 12/15-脂氧合酶活性对真菌相关性过敏性哮喘有负面影响。
Am J Physiol Lung Cell Mol Physiol. 2023 Aug 1;325(2):L104-L113. doi: 10.1152/ajplung.00090.2023. Epub 2023 May 30.
4
Role of the bone marrow vascular niche in chemotherapy for MLL-AF9-induced acute myeloid leukemia.骨髓血管龛在MLL-AF9诱导的急性髓系白血病化疗中的作用
Blood Sci. 2023 Apr 19;5(2):92-100. doi: 10.1097/BS9.0000000000000158. eCollection 2023 Apr.
5
Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19.几丁质酶 3 样蛋白 1 是一种治疗靶点，介导了衰老在 COVID-19 中的作用。
JCI Insight. 2021 Nov 8;6(21):e148749. doi: 10.1172/jci.insight.148749.
本文引用的文献
1
The chemokine CX3CL1/fractalkine regulates immunopathogenesis during fungal-associated allergic airway inflammation.趋化因子 CX3CL1/ fractalkine 调节真菌相关过敏性气道炎症中的免疫发病机制。
Am J Physiol Lung Cell Mol Physiol. 2021 Mar 1;320(3):L393-L404. doi: 10.1152/ajplung.00376.2020. Epub 2020 Dec 16.
2
Hyaluronan and halogen-induced airway hyperresponsiveness and lung injury.透明质酸和卤素诱导的气道高反应性和肺损伤。
Ann N Y Acad Sci. 2020 Nov;1479(1):29-43. doi: 10.1111/nyas.14415. Epub 2020 Jun 23.
3
The Role of New IL-1 Family Members (IL-36 and IL-38) in Atopic Dermatitis, Allergic Asthma, and Allergic Rhinitis.新型白细胞介素-1 家族成员（IL-36 和 IL-38）在特应性皮炎、过敏性哮喘和过敏性鼻炎中的作用。
Curr Allergy Asthma Rep. 2020 Jun 12;20(8):40. doi: 10.1007/s11882-020-00937-1.
4
The Fungal Cell Wall: , , and Species.真菌细胞壁：，，和物种。 （你提供的原文似乎不完整，请检查补充完整后以便能更准确翻译。）
Front Microbiol. 2020 Jan 9;10:2993. doi: 10.3389/fmicb.2019.02993. eCollection 2019.
5
IL-1RA regulates immunopathogenesis during fungal-associated allergic airway inflammation.白细胞介素-1 受体拮抗剂在真菌相关过敏性气道炎症中的免疫发病机制调节作用。
JCI Insight. 2019 Nov 1;4(21):129055. doi: 10.1172/jci.insight.129055.
6
Serum chitinase-like protein YKL-40 is linked to small airway function in children with asthmatic symptoms.血清几丁质酶样蛋白 YKL-40 与哮喘症状儿童的小气道功能相关。
Pediatr Allergy Immunol. 2019 Dec;30(8):803-809. doi: 10.1111/pai.13119. Epub 2019 Oct 2.
7
Chitinase-like protein YKL-40 correlates with inflammatory phenotypes, anti-asthma responsiveness and future exacerbations.几丁质酶样蛋白 YKL-40 与炎症表型、抗哮喘反应性和未来加重相关。
Respir Res. 2019 May 22;20(1):95. doi: 10.1186/s12931-019-1051-9.
8
YKL-40 and adult-onset asthma: Elevated levels in clusters with poorest outcome.YKL-40与成人起病型哮喘：在预后最差的亚组中水平升高。
J Allergy Clin Immunol Pract. 2019 Sep-Oct;7(7):2466-2468.e3. doi: 10.1016/j.jaip.2019.03.043. Epub 2019 Apr 4.
9
Chitinase 3-like 1 protein plays a critical role in respiratory syncytial virus-induced airway inflammation.几丁质酶 3 样蛋白 1 在呼吸道合胞病毒诱导的气道炎症中发挥关键作用。
Allergy. 2019 Apr;74(4):685-697. doi: 10.1111/all.13661. Epub 2018 Dec 4.
10
Interleukin 30 to Interleukin 40.白细胞介素 30 至白细胞介素 40。
J Interferon Cytokine Res. 2018 Oct;38(10):423-439. doi: 10.1089/jir.2018.0089.
Zotero 插件