Biophotonics Lab, Department of Applied Mechanics, Indian Institute of Technology Madras, Chennai, India.
Department of Pathology, Sri Ramachandra Medical College and Research Institute, SRIHER, Porur, Chennai, India.
J Biophotonics. 2021 May;14(5):e202000475. doi: 10.1002/jbio.202000475. Epub 2021 Feb 13.
Polarimetric imaging and image analysis have gained increased interest in soft tissue analysis at the cellular level. However, polarimetric imaging has widely been tested on thin tissue sections to provide reliable information correlated with histopathological findings. Polarimetric bulk tissue analysis always offered an overall assessment of various tissue optical properties for diagnosis. In this study, the histopathological correlation of bulk tissue polarimetry images for soft tissues is discussed. The first-hand information on the use of bulk tissue Mueller polarimetry and image analysis as an alternative to tissue histopathology is presented for surgically extracted colon and breast tissues.
偏振成像和图像分析在细胞水平的软组织分析中受到了越来越多的关注。然而，偏振成像已经广泛应用于薄组织切片，以提供与组织病理学发现相关的可靠信息。偏振体组织分析总是对各种组织光学特性进行全面评估，以进行诊断。本研究讨论了体组织偏振成像与组织病理学的相关性。本文介绍了使用体组织 Mueller 偏振测量和图像分析作为组织病理学替代方法的第一手资料，这些资料来自于手术切除的结肠和乳腺组织。
