Universidade Católica do Salvador, Departamento de Fisioterapia, Salvador, BA, Brasil.
Escola Bahiana de Medicina e Saúde Pública, Departamento de Pós-Graduação, Salvador, BA, Brasil.
Rev Soc Bras Med Trop. 2021 Jan 29;54:e06232020. doi: 10.1590/0037-8682-0623-2020. eCollection 2021.
Individuals with human T-cell lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) experience sensorimotor alterations, which can affect functional performance. Virtual reality (VR) videogaming is a therapeutic option, though there is scarce evidence for its use in this population. We aimed to investigate the therapeutic effects of a VR video game on functional mobility, balance, and gait speed in individuals with HAM/TSP.
We conducted a blinded, crossover clinical trial comprising 29 individuals with HAM/TSP and randomized them into two groups: (1) early therapy: rehabilitative protocol started immediately after the initial evaluation and (2) late therapy: rehabilitative protocol started 10 weeks later. We assessed all participants for balance using the Berg Balance Scale (BBS) scores, functional mobility using the Timed Up and Go (TUG) test, and gait speed using video camera and CvMob software. Differences were considered significant if p<0.05.
The early therapy group individuals presented with higher BBS scores (p=0.415), less TUG times (p=0.290), and greater gait speed (p=0.296) than the late therapy group individuals.
VR videogaming is a useful option for rehabilitative therapy in individuals with HAM/TSP; it positively affects balance, functional mobility, and gait speed.
人类 T 细胞嗜淋巴细胞病毒 1 相关的脊髓病/热带痉挛性截瘫（HAM/TSP）患者会出现感觉运动改变，这可能会影响其功能表现。虚拟现实（VR）视频游戏是一种治疗选择，但在该人群中使用的证据很少。我们旨在研究 VR 视频游戏对 HAM/TSP 患者的功能性移动、平衡和步速的治疗效果。
我们进行了一项盲法、交叉临床试验，纳入了 29 名 HAM/TSP 患者，并将他们随机分为两组：（1）早期治疗：康复方案在初始评估后立即开始；（2）晚期治疗：康复方案在 10 周后开始。我们使用 Berg 平衡量表（BBS）评分评估所有参与者的平衡能力，使用计时起立行走（TUG）测试评估功能性移动能力，使用摄像机和 CvMob 软件评估步速。如果 p 值<0.05，则认为差异具有统计学意义。
早期治疗组患者的 BBS 评分较高（p=0.415），TUG 时间较短（p=0.290），步速较快（p=0.296）。
VR 视频游戏是 HAM/TSP 患者康复治疗的一个有用选择；它对平衡、功能性移动和步速都有积极影响。
