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临床衰弱量表在高龄重症监护病房患者中的可靠性:一项欧洲前瞻性研究。

Reliability of the Clinical Frailty Scale in very elderly ICU patients: a prospective European study.

作者信息

Flaatten Hans, Guidet Bertrand, Andersen Finn H, Artigas Antonio, Cecconi Maurizio, Boumendil Ariane, Elhadi Muhammed, Fjølner Jesper, Joannidis Michael, Jung Christian, Leaver Susannah, Marsh Brian, Moreno Rui, Oeyen Sandra, Nalapko Yuriy, Schefold Joerg C, Szczeklik Wojciech, Walther Sten, Watson Ximena, Zafeiridis Tilemachos, de Lange Dylan W

机构信息

Department of Anaesthesia and Intensive Care, Dep of Clinical Medicine, Haukeland University Hospital Bergen Norway, University of Bergen, 5019, Bergen, Norway.

Sorbonne Université, INSERM, Institut Pierre Louis D'Epidémiologie Et de Santé Publique, Saint Antoine Hospital, AP-HP, Hôpital Saint-Antoine, Service de Réanimation, 75012, Paris, France.

出版信息

Ann Intensive Care. 2021 Feb 3;11(1):22. doi: 10.1186/s13613-021-00815-7.

Abstract

PURPOSE

Frailty is a valuable predictor for outcome in elderly ICU patients, and has been suggested to be used in various decision-making processes prior to and during an ICU admission. There are many instruments developed to assess frailty, but few of them can be used in emergency situations. In this setting the clinical frailty scale (CFS) is frequently used. The present study is a sub-study within a larger outcome study of elderly ICU patients in Europe (the VIP-2 study) in order to document the reliability of the CFS.

MATERIALS AND METHODS

From the VIP-2 study, 129 ICUs in 20 countries participated in this sub-study. The patients were acute admissions ≥ 80 years of age and frailty was assessed at admission by two independent observers using the CFS. Information was obtained from the patient, if not feasible, from the family/caregivers or from hospital files. The profession of the rater and source of data were recorded along with the score. Interrater variability was calculated using linear weighted kappa analysis.

RESULTS

1923 pairs of assessors were included and background data of patients were similar to the whole cohort (n = 3920). We found a very high inter-rater agreement (weighted kappa 0.86), also in subgroup analyses. The agreement when comparing information from family or hospital records was better than using only direct patient information, and pairs of raters from same profession performed better than from different professions.

CONCLUSIONS

Overall, we documented a high reliability using CFS in this setting. This frailty score could be used more frequently in elderly ICU patients in order to create a more holistic and realistic impression of the patient´s condition prior to ICU admission.

摘要

目的

衰弱是老年重症监护病房(ICU)患者预后的重要预测指标,有人建议在ICU入院前及入院期间的各种决策过程中使用该指标。目前已开发出多种评估衰弱的工具,但其中很少能用于紧急情况。在这种情况下,临床衰弱量表(CFS)被频繁使用。本研究是欧洲一项针对老年ICU患者的大型预后研究(VIP-2研究)的子研究,旨在证明CFS的可靠性。

材料与方法

来自VIP-2研究的20个国家的129个ICU参与了这项子研究。患者为80岁及以上的急性入院患者,入院时由两名独立观察者使用CFS评估衰弱情况。如果无法从患者处获取信息,则从家属/护理人员或医院档案中获取。记录评分者的职业、数据来源以及评分。使用线性加权kappa分析计算评分者间的变异性。

结果

纳入了1923对评估者,患者的背景数据与整个队列(n = 3920)相似。我们发现评分者间的一致性非常高(加权kappa为0.86),亚组分析结果也是如此。比较来自家属或医院记录的信息时的一致性优于仅使用患者直接信息时的一致性,且来自同一职业的评分者对的表现优于来自不同职业的评分者对。

结论

总体而言,我们证明了在这种情况下使用CFS具有很高的可靠性。该衰弱评分可更频繁地用于老年ICU患者,以便在ICU入院前对患者状况形成更全面、更现实的印象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c4/7859027/a55fb2a2c73b/13613_2021_815_Fig1_HTML.jpg

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