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经桡动脉入路门诊子宫动脉栓塞术的单中心经验:安全性、可行性、结局及早期重返率。

Single-System Experience With Outpatient Transradial Uterine Artery Embolization: Safety, Feasibility, Outcomes, and Early Rates of Return.

机构信息

Department of Radiology, Division of Interventional Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Medical Center, One Gustave L. Levy Pl, Box 1234, New York, NY 10029.

Division of Interventional Radiology, Emory University Hospital, Atlanta, GA.

出版信息

AJR Am J Roentgenol. 2021 Apr;216(4):975-980. doi: 10.2214/AJR.20.23343. Epub 2021 Feb 3.

DOI:10.2214/AJR.20.23343
PMID:33534624
Abstract

The purpose of this study was to assess feasibility and rate of patients returning to the hospital when a same-day discharge protocol is used for patients undergoing transradial uterine artery embolization (UAE) for symptomatic fibroids. A total of 374 patients who underwent transradial UAE with a same-day discharge protocol between April 2013 and June 2019, with documented follow-up, were included in this single-health-system retrospective study. Angiographic images and procedural reports were reviewed for technical success (defined as bilateral embolization). Electronic medical records were reviewed for patient and fibroid characteristics, adverse events, clinical success (defined as documented improvement in symptoms or patient satisfaction), and unplanned clinic visits, emergency department visits, and readmissions within 30 days of UAE. Univariate and multivariate analyses were used to identify risk factors for unplanned visits. Eight (2.1%) patients required conversion to inpatient stay (mean length of stay, 1.4 days; range, 1-3 days). The median postprocedure observation time was 3.7 hours (range, 1.1-12.5 hours). Technical success was achieved in 94.7% of patients, with 2.4% requiring crossover to the femoral artery for access. Clinical success was achieved in 86.0% of patients, with 6-month reductions in uterus and dominant leiomyoma volume of 30.4% and 42.9%, respectively. Rates of unplanned clinic visits, emergency department visits, and readmissions were 3.2%, 5.1%, and 0.5%, respectively. Patients with submucosal fibroids or pain as an indication for UAE were significantly more likely to have unplanned visits. Transradial UAE for symptomatic fibroids can be performed using a same-day discharge protocol with low rates of patients returning to the hospital. Submucosal location and pain as an indication for UAE were predictors of early return.

摘要

本研究旨在评估在因症状性子宫肌瘤行经桡动脉子宫动脉栓塞术(UAE)的患者中使用当日出院方案时患者返回医院的可行性和比率。这项单医疗系统回顾性研究纳入了 2013 年 4 月至 2019 年 6 月期间接受经桡动脉 UAE 并具有当日出院方案且有记录随访的 374 例患者。对血管造影图像和手术报告进行了技术成功(定义为双侧栓塞)评估。对电子病历进行了患者和肌瘤特征、不良事件、临床成功(定义为症状或患者满意度有记录改善)以及 UAE 后 30 天内的非计划就诊、急诊就诊和再入院评估。采用单变量和多变量分析来确定非计划就诊的风险因素。有 8 例(2.1%)患者需要转为住院治疗(平均住院时间 1.4 天;范围,1-3 天)。术后观察时间中位数为 3.7 小时(范围,1.1-12.5 小时)。94.7%的患者实现了技术成功,有 2.4%的患者需要交叉至股动脉进行入路。86.0%的患者实现了临床成功,术后 6 个月子宫和主要肌瘤体积分别减少 30.4%和 42.9%。非计划就诊、急诊就诊和再入院率分别为 3.2%、5.1%和 0.5%。黏膜下肌瘤或 UAE 适应证为疼痛的患者非计划就诊的可能性显著更高。对于症状性子宫肌瘤,行经桡动脉 UAE 可使用当日出院方案,患者返回医院的比例较低。黏膜下位置和 UAE 的适应证为疼痛是早期返回的预测因素。

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An update on uterine artery embolization for uterine leiomyomata and adenomyosis of the uterus.
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Br J Radiol. 2023 Mar;96(1143):20220121. doi: 10.1259/bjr.20220121. Epub 2022 Nov 25.