Salehi Mohammadgharib, Jalilian Nasrin, Salehi Ayoub, Ayazi Mojgan
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Glob J Health Sci. 2015 Dec 18;8(7):245-50. doi: 10.5539/gjhs.v8n7p245.
We decided to evaluate the efficacy and complications of uterine artery embolization (UAE) in patients with symptomatic uterine fibroids. Sixty-five premenopausal patients, without considering the fibroids size and its location, were treated by bilateral UAE. At baseline and after 3, 6, and 12 months MRI was obtained to determine the uterine length and fibroid diameter. In addition, symptoms of the patients were documented at these follow-up schedules. UAE was successful in 62 (95.4%) cases. Complete infarction rate of the fibroid was 83.1%. After 12 months, the uterine length showed a decrease of 55.7% (mean of 9.4 cm) and the diameter of the dominant fibroid revealed a decrease of 52.1% (mean of 3.4 cm). Menorrhagia improved in 45 cases (91.8%), abdominal mass in 24 cases (82.28%), urinary symptoms in 17 cases (85%), pelvic pain in 21 cases (84%), and dysmenorrhea in 25 cases (80.6%). At final follow-up performed after one year, complete infarction of the fibroma was demonstrated in 49 patients (83.1%). Two cases achieved successful pregnancy in the one year follow-up period. Five patients developed post-embolization syndrome which necessitated admission to the hospital. Twenty-two patients presented and complained of pain for which outpatient pain management was done. UAE was a successful treatment for uterine fibroids that preserved the uterus, had minimal complications, and required short hospitalization and recovery.
我们决定评估子宫动脉栓塞术(UAE)治疗有症状子宫肌瘤患者的疗效及并发症。65例绝经前患者接受了双侧UAE治疗,未考虑肌瘤大小及位置。在基线期以及3、6和12个月后进行磁共振成像(MRI)以测定子宫长度和肌瘤直径。此外,在这些随访时间记录患者症状。UAE成功62例(95.4%)。肌瘤完全梗死率为83.1%。12个月后,子宫长度减少55.7%(平均9.4厘米),主要肌瘤直径减少52.1%(平均3.4厘米)。月经过多改善45例(91.8%),腹部肿块改善24例(约82.28%),泌尿系统症状改善17例(85%),盆腔疼痛改善21例(84%),痛经改善25例(80.6%)。在一年后的最终随访中,49例患者(83.1%)显示肌瘤完全梗死。2例患者在一年随访期内成功妊娠。5例患者发生栓塞后综合征,需住院治疗。22例患者出现疼痛并进行了门诊疼痛处理。UAE是一种治疗子宫肌瘤的成功方法,可保留子宫,并发症少,住院时间短且恢复快。