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How gut microbes could drive brain disorders.

作者信息

Willyard Cassandra

出版信息

Nature. 2021 Feb;590(7844):22-25. doi: 10.1038/d41586-021-00260-3.

DOI:10.1038/d41586-021-00260-3
PMID:33536656
Abstract
摘要

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Elife. 2020 Feb 11;9:e53111. doi: 10.7554/eLife.53111.
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Potential roles of gut microbiome and metabolites in modulating ALS in mice.肠道微生物组和代谢物在调节小鼠 ALS 中的潜在作用。
Nature. 2019 Aug;572(7770):474-480. doi: 10.1038/s41586-019-1443-5. Epub 2019 Jul 22.
3
Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease.肠道到大脑的病理性 α-突触核蛋白的转神经元传播可模拟帕金森病。
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Front Pharmacol. 2025 May 15;16:1596469. doi: 10.3389/fphar.2025.1596469. eCollection 2025.
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The gut-brain axis in early Parkinson's disease: from prodrome to prevention.早期帕金森病中的肠-脑轴:从前驱症状到预防
J Neurol. 2025 May 21;272(6):413. doi: 10.1007/s00415-025-13138-5.
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Raffinose-metabolizing bacteria impair radiation-associated hematopoietic recovery the bile acid/FXR/NF-κB signaling pathway.棉子糖代谢细菌通过胆汁酸/FXR/NF-κB信号通路损害辐射相关的造血恢复。
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