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类风湿性多关节炎中红细胞、血小板及血清超氧化物歧化酶、谷胱甘肽过氧化物酶和过氧化氢酶的测定

[Assay of erythrocyte, platelet and serum superoxide dismutase, glutathione peroxidase and catalase in rheumatoid polyarthritis].

作者信息

Clerc D, Abella A, Bauer D, Baret A, Lindenbaum A, Bisson M, Leluc R, Massias P

机构信息

Service de Rhumatologie, Hôpital de Bicêtre, Le Kremlin-Bicêtre.

出版信息

Rev Rhum Mal Osteoartic. 1988 Jan;55(1):15-8.

PMID:3353671
Abstract

The authors present a study of superoxide dismutase, catalase and glutathione peroxidase in hemolysis product, platelets and serum of 23 patients with rheumatoid polyarthritis and 11 healthy subjects. The nature of the treatment enables to divide the 23 patients into 3 groups: group I (8 cases): no treatment; Group II (7 cases): steroid therapy alone; group III (8 cases): basic treatment associated (3 cases) or not (5 cases) to steroid therapy. Statistical analysis shows no significant difference, whatever the environment and the treatment contemplated. The significance of these results is discussed and compared with literature data concerning only enzymatic activities and not the blood levels as in the present study.

摘要

作者对23例类风湿性多关节炎患者和11名健康受试者的溶血产物、血小板及血清中的超氧化物歧化酶、过氧化氢酶和谷胱甘肽过氧化物酶进行了研究。根据治疗方式,可将23例患者分为3组:第一组(8例):未治疗;第二组(7例):仅接受类固醇治疗;第三组(8例):基础治疗联合(3例)或未联合(5例)类固醇治疗。统计分析表明,无论在何种环境及考虑何种治疗方式下,均无显著差异。本文对这些结果的意义进行了讨论,并与仅涉及酶活性而非像本研究中涉及血液水平的文献数据进行了比较。

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