术后抗生素在预防单纯性阑尾炎手术部位感染中的作用。
The role of postoperative antibiotics in preventing surgical site infections in uncomplicated appendicitis.
作者信息
Abounozha Sabry, Ibrahim Rashid, Alshehri Faisal Mohammed, Nawara Hossam, Alawad Awad
机构信息
Northumbria Healthcare NHS Foundation Trust, Northumbria, UK.
University Hospitals Plymouth NHS Trust, Plymouth, UK.
出版信息
Ann Med Surg (Lond). 2021 Jan 19;62:203-206. doi: 10.1016/j.amsu.2021.01.037. eCollection 2021 Feb.
A best evidence topic has been constructed using a described protocol. The three-part question addressed was: In patients who underwent appendicectomy for uncomplicated appendicitis is the use of postoperative antibiotics associated with lower rates of surgical site infections? The search has been devised and 6 studies were deemed to be suitable to answer the question. The outcome assessed was the efficiency of postoperative antibiotic therapy in decreasing the rate of surgical site infections in uncomplicated appendicitis. Authors recommend against the use of postoperative antibiotics based on the supported evidence. Hence, its usage was not associated with lower rates of surgical site infections. On the contrary, it might increase the cost, postoperative morbidity and length of stay.
一个最佳证据主题是按照既定方案构建的。所提出的三部分问题是：在因单纯性阑尾炎接受阑尾切除术的患者中，术后使用抗生素是否与手术部位感染率较低相关？已制定了检索策略，6项研究被认为适合回答该问题。评估的结果是术后抗生素治疗在降低单纯性阑尾炎手术部位感染率方面的有效性。基于所提供的证据，作者建议不使用术后抗生素。因此，其使用与较低的手术部位感染率无关。相反，它可能会增加成本、术后发病率和住院时间。
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