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对一家高手术量单中心全髋关节置换翻修病因的流行病学分析。

An epidemiological analysis of revision aetiologies in total hip arthroplasty at a single high-volume centre.

作者信息

Kerzner Benjamin, Kunze Kyle N, O'Sullivan Michael B, Pandher Karan, Levine Brett R

机构信息

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA.

Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.

出版信息

Bone Jt Open. 2021 Jan 3;2(1):16-21. doi: 10.1302/2633-1462.21.BJO-2020-0171.R1. eCollection 2021 Jan.

Abstract

AIMS

Advances in surgical technique and implant design may influence the incidence and mechanism of failure resulting in revision total hip arthroplasty (rTHA). The purpose of the current study was to characterize aetiologies requiring rTHA, and to determine whether temporal changes existed in these aetiologies over a ten-year period.

METHODS

All rTHAs performed at a single institution from 2009 to 2019 were identified. Demographic information and mode of implant failure was obtained for all patients. Data for rTHA were stratified into two time periods to assess for temporal changes: 2009 to 2013, and 2014 to 2019. Operative reports, radiological imaging, and current procedural terminology (CPT) codes were cross-checked to ensure the accurate classification of revision aetiology for each patient.

RESULTS

In all, 2,924 patients with a mean age of 64.6 years (17 to 96) were identified. There were 1,563 (53.5%) female patients, and the majority of patients were Caucasian (n = 2,362, 80.8%). The three most frequent rTHA aetiologies were infection (27.2%), aseptic loosening (25.2%), and wear (15.2%). The frequency of rTHA for adverse local tissue reaction (ALTR) was significantly greater from 2014 to 2019 (4.7% vs 10.0%; p < 0.001), while the frequency of aseptic loosening was significantly greater from 2009 to 2013 (28.6% vs 21.9%; p < 0.001).

CONCLUSION

Periprosthetic joint infection was the most common cause for rTHA in the current cohort of patients. Complications associated with ALTR necessitating rTHA was more frequent between 2014 to 2019, while aseptic loosening necessitating rTHA was significantly more frequent between 2009 to 2013. Optimizing protocols for prevention and management of infection and ALTR after THA may help to avoid additional financial burden to institutions and healthcare systems.Cite this article: 2020;2(1):16-21.

摘要

目的

手术技术和植入物设计的进步可能会影响导致翻修全髋关节置换术(rTHA)失败的发生率和机制。本研究的目的是确定需要进行rTHA的病因,并确定在十年期间这些病因是否存在时间变化。

方法

确定了2009年至2019年在单一机构进行的所有rTHA手术。获取了所有患者的人口统计学信息和植入物失败模式。将rTHA的数据分为两个时间段以评估时间变化:2009年至2013年和2014年至2019年。对手术报告、影像学检查和当前手术操作术语(CPT)代码进行交叉核对,以确保对每位患者的翻修病因进行准确分类。

结果

共识别出2924例患者,平均年龄64.6岁(17至96岁)。有1563例(53.5%)女性患者,大多数患者为白种人(n = 2362,80.8%)。rTHA最常见的三种病因是感染(27.2%)、无菌性松动(25.2%)和磨损(15.2%)。2014年至2019年因局部组织不良反应(ALTR)导致的rTHA发生率显著更高(4.7%对10.0%;p < 0.001),而2009年至2013年无菌性松动的发生率显著更高(28.6%对21.9%;p < 0.001)。

结论

在当前队列患者中,假体周围关节感染是rTHA最常见的原因。2014年至2019年期间,因ALTR需要进行rTHA的并发症更为常见,而2009年至2013年期间,因无菌性松动需要进行rTHA的情况显著更为常见。优化THA后感染和ALTR的预防和管理方案可能有助于避免给机构和医疗系统带来额外的经济负担。引用本文:2020;2(1):16 - 21。

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