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直肠癌前切除术中行预防性回肠造口术与末端回肠造口术的疗效及成本-效果比较研究

Comparative study between ghost ileostomy and defunctioning ileostomy in terms of morbidity and cost-effectiveness in low anterior resection for rectal cancer.

机构信息

Department of General Surgery, VKF American Hospital, Guzelbahce Street, No:20, Sisli, Istanbul, Turkey.

Department of General Surgery, School of Medicine, Koc University, Istanbul, Turkey.

出版信息

Langenbecks Arch Surg. 2021 Mar;406(2):339-347. doi: 10.1007/s00423-021-02089-w. Epub 2021 Feb 4.

DOI:10.1007/s00423-021-02089-w
PMID:33537875
Abstract

PURPOSE

The aim of this study was to compare ghost ileostomy (GI) and defunctioning ileostomy (DI) in patients who underwent low anterior resection (LAR) for rectal cancer in terms of postoperative morbidity, rehospitalization rates, and total costs.

METHODS

Patients with an anastomosis level between 5 and 10 cm from the anal verge after LAR were analyzed retrospectively. Clinical characteristics, operative outcomes, postoperative morbidity, rehospitalization rates, and total costs were compared.

RESULTS

A total of 123 patients were enrolled as follows: 42 patients in the GI group and 81 patients in the DI group. Anastomotic leakage (AL) was identified in three patients who underwent GI, and in all of them, GI was easily converted to DI. There were 96.3% of the patients with DI rehospitalized at least one time because of surgery-related and/or stoma-related complications or stoma closure. When we did not take into account the patients who were rehospitalized for stoma closure, the rates of rehospitalization were 4.7% and 22.2% in the GI and DI groups, respectively (P= 0.01). The mean total costs calculated by removing additional surgical procedures and adding all of the rehospitalization costs were 25,767 USD and 41,875 USD in the GI and DI groups, respectively (P= 0.0001).

CONCLUSION

GI may be a safe and cost-effective method in patients who underwent LAR with low or medium risk factors for AL. It is possible to avoid unnecessary ileostomy and reduce unwanted outcomes due to it, such as postoperative complications, rehospitalizations, and increased total costs by performing GI.

摘要

目的

本研究旨在比较低位前切除术(LAR)治疗直肠癌患者中 ghost ileostomy(GI)和 defunctioning ileostomy(DI)在术后发病率、再住院率和总费用方面的差异。

方法

回顾性分析吻合口位于肛缘上 5-10cm 的 LAR 患者。比较临床特征、手术结果、术后发病率、再住院率和总费用。

结果

共纳入 123 例患者:GI 组 42 例,DI 组 81 例。GI 组有 3 例发生吻合口漏,均容易转换为 DI。81.0%的 DI 患者因手术相关和/或造口相关并发症或造口关闭而至少再住院一次。当我们不考虑因造口关闭而再住院的患者时,GI 和 DI 组的再住院率分别为 4.7%和 22.2%(P=0.01)。去除额外手术程序并添加所有再住院费用后,GI 和 DI 组的总费用分别为 25767 美元和 41875 美元(P=0.0001)。

结论

对于低位前切除术治疗低位和中危吻合口漏风险的患者,GI 可能是一种安全且具有成本效益的方法。通过实施 GI,可以避免不必要的造口术,并减少因造口术引起的术后并发症、再住院和增加总费用等不良后果。

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本文引用的文献

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BMJ Open. 2020 Oct 15;10(10):e038930. doi: 10.1136/bmjopen-2020-038930.
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Virtual ileostomy in elective colorectal surgery: a systematic review of the literature.择期结直肠手术中的虚拟回肠造口术:文献系统综述
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Anastomotic Leakage in Rectal Surgery: Role of the Ghost Ileostomy.
直肠癌术后行造口还纳术时,预防性回肠袢式造口与单纯末端回肠造口的比较:一项系统评价和荟萃分析。
Surg Innov. 2023 Aug;30(4):501-516. doi: 10.1177/15533506231169066. Epub 2023 Apr 4.
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Ghost Ileostomy: Safe and Cost-effective Alternative to Ileostomy After Rectal Resection for Deep Infiltrating Endometriosis.肠造口术后肠气肿:直肠深部浸润性子宫内膜异位症直肠切除术后肠造口术的安全且具成本效益的替代方法。
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