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皮肤科医生对中度银屑病定义的看法:加拿大中度银屑病调查。

Dermatologists' Perspectives on Defining Moderate Psoriasis: The Canadian Moderate Psoriasis Survey.

出版信息

J Drugs Dermatol. 2021 Feb 1;20(2):126-132. doi: 10.36849/JDD.5531.

Abstract

BACKGROUND

Psoriasis is commonly classified as either mild or moderate to severe, without specific parameters to differentiate moderate versus severe disease. This may lead to patients with moderate psoriasis being underrecognized and undertreated.

OBJECTIVE

An online survey was conducted to assess Canadian dermatologists’ perspectives on the definition and treatment of psoriasis.

METHOD

Dermatologists included in the survey were regional and national leaders with expertise in psoriasis. Questions were developed based on feedback from a steering committee of Canadian dermatologists.

RESULTS

Of 88 dermatologists contacted, 69 responded; 42.0% were in practice for >20 years. Most dermatologists reported using the percentage of psoriasis-affected body surface area (BSA) to describe disease severity (90.8% for moderate and 87.5% for severe psoriasis). The lower and upper median cutoffs for moderate psoriasis were reported as 5.0% and 10.0% for BSA and 7.0 and 11.5 for the Dermatology Life Quality Index. Most dermatologists also consider psoriasis location (eg, palms, scalp, genital area, face) as an important indicator of disease severity. The majority of Canadian dermatologists (87.5%) identified access to treatment as one of the biggest challenges for patients with moderate psoriasis. Most dermatologists estimated that ≤40% of their patients with moderate plaque psoriasis were being treated with traditional oral systemics, targeted oral systemics, or biologics.

CONCLUSIONS

This is the first survey of Canadian dermatologists on moderate psoriasis. Efforts are needed to implement a clinically useful definition of moderate plaque psoriasis to improve patient care and to raise awareness of the definition among regulatory agencies and reimbursement authorities. J Drugs Dermatol. 2021;20(2):126-132. doi:10.36849/JDD.5531.

摘要

背景

银屑病通常分为轻度或中度至重度,没有特定的参数来区分中度和重度疾病。这可能导致中度银屑病患者被低估和治疗不足。

目的

进行了一项在线调查,以评估加拿大皮肤科医生对银屑病定义和治疗的看法。

方法

参与调查的皮肤科医生是在银屑病方面具有专业知识的区域和国家领导人。问题是根据加拿大皮肤科医生指导委员会的反馈制定的。

结果

在联系的 88 名皮肤科医生中,有 69 名做出了回应;42.0%的医生行医时间超过 20 年。大多数皮肤科医生报告使用银屑病受累体表面积(BSA)的百分比来描述疾病严重程度(中度银屑病为 90.8%,重度银屑病为 87.5%)。中度银屑病的下和上中位数截止值报告为 BSA 的 5.0%和 10.0%,皮肤病生活质量指数(DLQI)为 7.0%和 11.5%。大多数皮肤科医生还认为银屑病的位置(如手掌、头皮、生殖器、面部)是疾病严重程度的一个重要指标。大多数加拿大皮肤科医生(87.5%)认为中度银屑病患者面临的最大挑战之一是获得治疗。大多数皮肤科医生估计,他们中度斑块状银屑病患者中,只有 ≤40%的患者接受了传统口服系统药物、靶向口服系统药物或生物制剂治疗。

结论

这是对加拿大皮肤科医生进行的首次中度银屑病调查。需要努力制定一个临床有用的中度斑块状银屑病定义,以改善患者的护理,并提高监管机构和报销机构对该定义的认识。J 皮肤病学杂志。2021;20(2):126-132。doi:10.36849/JDD.5531.

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