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恶心与大脑:化学感受器触发区进入分子时代。

Nausea and the Brain: The Chemoreceptor Trigger Zone Enters the Molecular Age.

机构信息

Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Pharmacology and Therapeutics Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Neuron. 2021 Feb 3;109(3):391-393. doi: 10.1016/j.neuron.2021.01.004.

DOI:10.1016/j.neuron.2021.01.004
PMID:33539771
Abstract

Area postrema in brainstem has long been known to trigger emesis by detecting blood-borne toxins and pathogens. In this issue, Zhang and colleagues provide a single-cell molecular atlas of this region, opening new possibilities for harnessing its neurons in vivo.

摘要

延脑的最后区长期以来一直被认为可以通过检测血液中的毒素和病原体来引发呕吐。在本期杂志中,Zhang 及其同事提供了该区域的单细胞分子图谱,为在体内利用其神经元开辟了新的可能性。

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