通过X射线图像分割确定实验性糖尿病和卵巢切除小鼠的股骨骨密度变化。
Femur absorptiometry changes determined by X-ray image segmentation in mice under experimental diabetes and ovariectomy.
作者信息
Flores-Reyes Mario, Torres-García Eugenio, Oros-Pantoja Rigoberto, Díaz-Sánchez Luis Enrique, Mercado-Quintero Alfredo V, Medina-Velázquez Luis Alberto
机构信息
Facultad de Medicina, Universidad Autónoma del Estado de México, Toluca, México, Mexico.
Facultad de Medicina, Universidad Autónoma del Estado de México, Toluca, México, Mexico.
出版信息
Appl Radiat Isot. 2021 Apr;170:109608. doi: 10.1016/j.apradiso.2021.109608. Epub 2021 Jan 24.
AIM
The aim of the present work was to determine if both ovariectomy (OVX) and type 2 diabetes mellitus (T2DM) can change X-ray absorptiometry until reach the osteoporosis condition.
RESULTS
The segmentation allowed us to quantitatively determine the X-ray absorption in the femurs of mice subjected to OVX, T2DM and both pathologies together.
CONCLUSIONS
The test subjects suffering from the mentioned pathologies separately or together, did not reach the osteoporosis condition when they were 30 weeks old.
目的
本研究的目的是确定卵巢切除术（OVX）和2型糖尿病（T2DM）是否都会改变骨密度测定，直至达到骨质疏松状态。
结果
通过分割，我们能够定量测定接受卵巢切除术、2型糖尿病以及两种病理情况同时存在的小鼠股骨的X线吸收情况。
结论
患有上述单一或合并病理情况的受试对象在30周龄时未达到骨质疏松状态。
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