Robotics and Mechatronics Systems Research Group, School of Engineering and Informatics, University of Sussex, Brighton BN1 9RH, UK.
School of Water, Energy and Environment, Cranfield University, Bedford MK43 0AL, UK.
Sensors (Basel). 2021 Feb 2;21(3):999. doi: 10.3390/s21030999.
Heart rate monitoring is the predominant quantitative health indicator of a newborn in the delivery room. A rapid and accurate heart rate measurement is vital during the first minutes after birth. Clinical recommendations suggest that electrocardiogram (ECG) monitoring should be widely adopted in the neonatal intensive care unit to reduce infant mortality and improve long term health outcomes in births that require intervention. Novel non-contact electrocardiogram sensors can reduce the time from birth to heart rate reading as well as providing unobtrusive and continuous monitoring during intervention. In this work we report the design and development of a solution to provide high resolution, real time electrocardiogram data to the clinicians within the delivery room using non-contact electric potential sensors embedded in a neonatal intensive care unit mattress. A real-time high-resolution electrocardiogram acquisition solution based on a low power embedded system was developed and textile embedded electrodes were fabricated and characterised. Proof of concept tests were carried out on simulated and human cardiac signals, producing electrocardiograms suitable for the calculation of heart rate having an accuracy within ±1 beat per minute using a test ECG signal, ECG recordings from a human volunteer with a correlation coefficient of ~ 87% proved accurate beat to beat morphology reproduction of the waveform without morphological alterations and a time from application to heart rate display below 6 s. This provides evidence that flexible non-contact textile-based electrodes can be embedded in wearable devices for assisting births through heart rate monitoring and serves as a proof of concept for a complete neonate electrocardiogram monitoring system.
心率监测是分娩室中新生儿的主要量化健康指标。在出生后的最初几分钟内,快速准确地测量心率至关重要。临床建议表明,应在新生儿重症监护病房广泛采用心电图(ECG)监测,以降低婴儿死亡率并改善需要干预的分娩的长期健康结果。新型非接触式心电图传感器可以减少从出生到心率读数的时间,同时在干预期间提供不引人注目的连续监测。在这项工作中,我们报告了一种解决方案的设计和开发,该解决方案使用嵌入新生儿重症监护病房床垫中的非接触式电位传感器,为分娩室中的临床医生提供高分辨率、实时心电图数据。开发了一种基于低功耗嵌入式系统的实时高分辨率心电图采集解决方案,并制造和表征了纺织嵌入式电极。对模拟和人体心脏信号进行了概念验证测试,使用测试 ECG 信号产生了适合计算心率的心电图,其精度在±1 次/分钟以内,使用人类志愿者的 ECG 记录,相关系数约为 87%,证明了对波形的准确逐拍形态再现,没有形态改变,从应用到心率显示的时间低于 6 秒。这表明,灵活的非接触式基于纺织品的电极可以嵌入可穿戴设备中,通过心率监测来辅助分娩,并为完整的新生儿心电图监测系统提供了概念验证。