Williams Emma, Ascherl Rudolf, Gaertner Vincent D, Sibrecht Greta, Kurul Serife, Herrmann Marie-Louise, Szakmar Eniko, Raffaeli Genny, Bresesti Ilia, Jost Kerstin
Department of Women and Children's Health, Faculty of Life Sciences & Medicine, King's College London, London, UK.
Department of Neonatology, Hospital for Children and Adolescents, University of Leipzig Medical Center, Leipzig, Germany.
J Clin Monit Comput. 2025 Jun 27. doi: 10.1007/s10877-025-01310-1.
Vital sign monitoring plays a pivotal role in assessing and managing the clinical condition of vulnerable newborn infants in the delivery room and in the neonatal intensive care unit (NICU), with advancements in technology over the last years paving the way for newer and less invasive monitoring techniques.
We conducted a narrative review of the literature in PubMed, Embase, GoogleScholar, and ClinicalTrials.gov. to describe newer technologies in neonatal monitoring of heart rate and oxygen saturation including secondary data-use, focusing also on promising studies which are currently underway.
Innovations such as photoplethysmography, wireless skin sensors, spectroscopy and tremolo sonification can provide a continuous and comprehensive assessment of neonatal vital sign monitoring, including heart rate and oxygen saturations, allowing for the enhancement of early detection of potential complications. Moreover advanced mathematical models, such as heart rate characteristic variability and closed loop automated systems, have shown promise in processing and storing vast amounts of data, aiding in the early prediction of adverse clinical outcomes, supporting decision-making and guiding the development of future studies.
As the field of vital sign monitoring in the NICU continues to evolve, it is essential to address challenges related to novel modalities, data privacy, algorithm accuracy, and seamless integration into existing healthcare systems. By harnessing the potential of innovative technologies, the future of vital sign monitoring in the NICU promises improved neonatal outcomes, enhanced healthcare delivery and facilitation of individualisation of care.
生命体征监测在产房和新生儿重症监护病房（NICU）评估和管理脆弱新生儿的临床状况方面发挥着关键作用，过去几年技术的进步为更新的、侵入性更小的监测技术铺平了道路。
我们对PubMed、Embase、GoogleScholar和ClinicalTrials.gov上的文献进行了叙述性综述，以描述新生儿心率和血氧饱和度监测中的新技术，包括二次数据使用，同时也关注目前正在进行的有前景的研究。
诸如光电容积脉搏波描记法、无线皮肤传感器、光谱学和震颤声化等创新技术可以对新生儿生命体征监测进行连续和全面的评估，包括心率和血氧饱和度，从而有助于加强对潜在并发症的早期检测。此外，先进的数学模型，如心率特征变异性和闭环自动化系统，在处理和存储大量数据方面显示出前景，有助于早期预测不良临床结局，支持决策制定并指导未来研究的开展。
随着NICU生命体征监测领域的不断发展，应对与新监测方式、数据隐私、算法准确性以及无缝集成到现有医疗系统相关的挑战至关重要。通过利用创新技术的潜力，NICU生命体征监测的未来有望改善新生儿结局、提高医疗服务质量并促进个性化护理。
