Rösler H D, Kleinpeter U, Gehrke R, Hinz G, Krause G
Psychiatr Neurol Med Psychol (Leipz). 1977 Jun;29(6):350-9.
The administration, in a double blind experiment, of piracetam to two homogeneous groups of 32 and 34 eight- to twelve-year-old brain-injured special education children lacking normal mental ability, where the daily doses administered for a period of thirteen weeks were 3 tablets or 1.2 g (administered to second and third graders) and 5 tablets or 2.0 g (administered to fourth graders), respectively, did not produce a lasting effect upon the capacity to acquire and apply knowledge, the concentration power, the proficiency level, and the behavior shown by pupils during and out of school hours. On the other hand, there was observed, in patients receiving placebos, a nonsignificant tendency toward improvement in physical well-being, so that the effect produced by the drug may here be considered to be a negative one.
在一项双盲实验中，对两组各有32名和34名8至12岁脑损伤特殊教育儿童（智力低于正常水平）进行了吡拉西坦给药。其中，13周期间，二年级和三年级学生每日服用3片或1.2克，四年级学生每日服用5片或2.0克。结果显示，该药对学生获取和应用知识的能力、注意力、熟练程度以及在校内外的行为均未产生持久影响。另一方面，在接受安慰剂的患者中，观察到身体状况有不显著的改善趋势，因此，该药在此处产生的影响可被视为负面的。
