不同胸外按压深度对窒息仔猪颈总动脉血流和血压的影响。
Effects of varying chest compression depths on carotid blood flow and blood pressure in asphyxiated piglets.
机构信息
Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Steiermark, Austria.
Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
出版信息
Arch Dis Child Fetal Neonatal Ed. 2021 Sep;106(5):553-556. doi: 10.1136/archdischild-2020-319473. Epub 2021 Feb 4.
BACKGROUND
Current neonatal resuscitation guidelines recommend chest compressions (CCs) should be delivered to a depth of approximately 1/3 of the anterior-posterior (AP) chest diameter. The aim of the study was to investigate the haemodynamic effects of different CC depths in a neonatal piglet model.
METHODS
CCs were performed with an automated CC machine with 33%, 40% and 25% AP chest diameter in all piglets in the same order for a duration of 3 min each.
RESULTS
Eight newborn piglets (age 1-3 days, weight 1.7-2.3 kg) were included in the study. Carotid blood flow (CBF) and systolic blood pressure were the highest using a CC depth of 40% AP chest diameter (19.3±7.5 mL/min/kg and 58±32 mm Hg).
CONCLUSION
CC depth influences haemodynamic parameters in asphyxiated newborn piglets during cardiopulmonary resuscitation. The highest CBF and systolic blood pressure were achieved using a CC depth of 40% AP chest diameter.
TRIAL REGISTRATION NUMBER
PCTE0000148.
背景
目前的新生儿复苏指南建议胸外按压（CCs）的深度应达到前后（AP）胸径的约 1/3。本研究旨在探讨不同 CC 深度对新生仔猪模型血流动力学的影响。
方法
所有仔猪均采用自动 CC 机，按相同顺序进行 33%、40%和 25%AP 胸径 CC，每次持续 3 分钟。
结果
本研究纳入了 8 只新生仔猪（1-3 天龄，体重 1.7-2.3kg）。使用 40%AP 胸径 CC 时，颈动脉血流量（CBF）和收缩压最高（19.3±7.5mL/min/kg 和 58±32mmHg）。
结论
CC 深度影响窒息新生仔猪心肺复苏期间的血流动力学参数。使用 40%AP 胸径 CC 时可获得最高的 CBF 和收缩压。
注册号
PCTE0000148。
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