Vijay Vathsalya, Alam Md Shahid, Subramanian Nirmala, Krishnakumar Subramanian, Biswas Jyotirmay, Mukherjee Bipasha
Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, India.
Oman J Ophthalmol. 2020 Nov 2;13(3):129-135. doi: 10.4103/ojo.OJO_130_2019. eCollection 2020 Sep-Dec.
To study the clinical profile and management outcomes of periocular basal cell carcinoma (BCC).
A retrospective analysis of all histopathologically proven cases of BCC between 1995 and 2015 was done. The demographic data, clinical presentation, histopathological subtype, and management outcomes were analyzed.
We had a total of 185 malignant eyelid tumors during the study period, out of which 37 (20%) were BCC. Thirty-two (86.5%) out of 37 cases were primary BCC. The mean age was 63.3 years. Pigmented ulcerative lesion (14, 38%), lower eyelid (19, 51%), and nodular BCC (15, 40%) were the most common presentation, periocular site, and histological subtype, respectively. 28 patients underwent excision under frozen section with an average tumor-free margin of 3.5 mm. Mean follow-up period was 18.78 months. Recurrence rate of 0% and 3.1% was noted in primary and recurrent BCC, respectively.
Periocular BCC commonly presents as pigmented ulcerative lesion in the lower lid. Excision biopsy under frozen section with an average tumor-free margin of 3.5 mm offers cure in most cases.
研究眼周基底细胞癌(BCC)的临床特征及治疗效果。
对1995年至2015年间所有经组织病理学证实的BCC病例进行回顾性分析。分析人口统计学数据、临床表现、组织病理学亚型及治疗效果。
研究期间共185例恶性眼睑肿瘤,其中37例(20%)为BCC。37例中32例(86.5%)为原发性BCC。平均年龄63.3岁。色素性溃疡性病变(14例,38%)、下眼睑(19例,51%)和结节型BCC(15例,40%)分别是最常见的表现、眼周部位及组织学亚型。28例患者在冰冻切片下进行切除,平均切缘无瘤宽度为3.5mm。平均随访期为18.78个月。原发性和复发性BCC的复发率分别为0%和3.1%。
眼周BCC通常表现为下眼睑色素性溃疡性病变。在冰冻切片下进行切除活检,平均切缘无瘤宽度为3.5mm,多数情况下可治愈。