Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, U.S.A.
Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, U.S.A.
Laryngoscope. 2021 Sep;131(9):E2594-E2598. doi: 10.1002/lary.29420. Epub 2021 Feb 5.
OBJECTIVE/HYPOTHESIS: The Nasal Obstruction Symptom Evaluation (NOSE) is a disease specific quality of life instrument developed and validated in adults. The objective of this study is to evaluate the validity of the NOSE scale for pediatric nasal obstruction. We also examined the effect of septoplasty with bilateral inferior turbinate reduction in this population.
A validation study at a tertiary care children's hospital.
Thirty-eight pediatric patients who underwent septoplasty and bilateral inferior turbinate reduction between 2014 and 2018 were included. Patients were administered the NOSE instrument on the day of their clinic evaluation, the day of surgery, and at their 6 to 8-week post-operative appointment. A sample of 40 pediatric patients with non-rhinologic complaints was also included. Confirmatory factor analysis was performed to evaluate the factorial validity of the NOSE instrument.
Of the 78 patients included, the mean age was 15.4 years (SD 3.4). In the confirmatory factor analysis, factor loadings were all significant and ranged from 0.95 to 0.99. Internal consistency reliability using Omega and maximal reliability H indices were well above recommended standards (Omega = 0.983 and maximal H = 0.988). Test-retest reliability was also adequate. Mean NOSE scores significantly improved following surgery (from 96.7 [SD 6.2] to 8.8 [SD 7.8]; mean difference = -87.9; 95% CI: -84.5, -91.3; P < .001). Similar improvements were observed across age groups.
The NOSE scale is a valid and reliable quality of life instrument for pediatric patients with nasal obstruction. Nasal septoplasty with bilateral turbinate reduction substantially improved symptoms of nasal obstruction.
4 Laryngoscope, 131:E2594-E2598, 2021.
目的/假设：鼻腔阻塞症状评估（NOSE）是一种专为成人开发并验证的特定于疾病的生活质量工具。本研究的目的是评估 NOSE 量表在小儿鼻塞中的有效性。我们还研究了鼻中隔成形术联合双侧下鼻甲减少术对此类人群的影响。
在一家三级儿童保健医院进行的验证研究。
纳入 2014 年至 2018 年间接受鼻中隔成形术和双侧下鼻甲减少术的 38 例小儿患者。患者在就诊当天、手术当天以及术后 6 至 8 周进行 NOSE 量表评估。还纳入了 40 例非鼻科疾病的儿科患者作为样本。进行验证性因子分析以评估 NOSE 量表的因子有效性。
在 78 例患者中，平均年龄为 15.4 岁（SD 3.4）。在验证性因子分析中，因子负荷均显著，范围为 0.95 至 0.99。使用 Omega 和最大可靠性 H 指数的内部一致性可靠性均远高于推荐标准（Omega = 0.983 和最大 H = 0.988）。测试-重测可靠性也足够。手术治疗后，NOSE 评分明显改善（从 96.7[SD 6.2]降至 8.8[SD 7.8]；平均差值=-87.9；95%置信区间：-84.5，-91.3；P<.001）。各年龄组均观察到类似的改善。
NOSE 量表是一种有效且可靠的生活质量工具，适用于患有鼻塞的小儿患者。鼻中隔成形术联合双侧下鼻甲减少术可显著改善鼻塞症状。
4 级喉镜，131：E2594-E2598，2021 年。
