Manteghi Alexander, Din Hena, Bundogji Nour, Leuin Shelby C
Division of Pediatric Otolaryngology, Rady Children's Hospital, 3020 Children's Way, San Diego, CA 92123, USA; University of California San Diego School of Medicine, 9500 Gilman Drive, San Diego, CA 92093, USA.
Division of Pediatric Otolaryngology, Rady Children's Hospital, 3020 Children's Way, San Diego, CA 92123, USA.
Int J Pediatr Otorhinolaryngol. 2018 Aug;111:16-20. doi: 10.1016/j.ijporl.2018.05.016. Epub 2018 May 25.
This study assessed disease-specific quality-of-life outcomes among pediatric patients undergoing septoplasty or functional septorhinoplasty. The Nasal Obstruction Symptom Evaluation (NOSE) score was obtained pre- and post-operatively. Additional analyses determined whether demographics, nasal trauma, prior nasal surgery, or allergic rhinitis history affected NOSE scores.
Patients undergoing septoplasty or functional septorhinoplasty were evaluated prospectively at a tertiary children's hospital. NOSE scores were assessed pre- and post-operatively. Change in NOSE score was analyzed using the Wilcoxon Signed Rank test, while multiple regression analysis evaluated factors associated with NOSE score change.
136 patients (mean age 15.7 ± 2.1 years) were evaluated; 52 (38.2%) underwent septoplasty while 84 (61.8%) underwent functional septorhinoplasty. Mean follow-up was 3.6 ± 5.1 months. There was a statistically significant decrease in NOSE score from pre-operative septoplasty and functional septorhinoplasty: median = 75 to post-operative septoplasty: median = 20 (z = -5.9, p < 0.001) and functional septorhinoplasty: median = 15 (z = -7.9, p < 0.001). Gender, age, nasal trauma, prior nasal surgery, and allergic rhinitis did not have a significant effect on NOSE score change for either group. Additional surgery at the time of procedure was not a confounding variable in the relationship between surgery type and NOSE score. A NOSE Scale reliability analysis demonstrated high internal consistency with Cronbach's α of 0.83 across septoplasty and functional septorhinoplasty patients.
There was significant improvement in disease-specific quality-of-life in pediatric patients undergoing septoplasty or functional septorhinoplasty. Gender, nasal trauma, prior nasal surgery, and allergic rhinitis did not significantly affect NOSE scores in either group.
本研究评估了接受鼻中隔成形术或功能性鼻中隔鼻成形术的儿科患者的疾病特异性生活质量结果。术前和术后均获得鼻阻塞症状评估（NOSE）评分。进一步分析确定人口统计学特征、鼻外伤、既往鼻手术或过敏性鼻炎病史是否会影响NOSE评分。
在一家三级儿童医院对接受鼻中隔成形术或功能性鼻中隔鼻成形术的患者进行前瞻性评估。术前和术后均评估NOSE评分。使用Wilcoxon符号秩检验分析NOSE评分的变化，同时多元回归分析评估与NOSE评分变化相关的因素。
共评估了136例患者（平均年龄15.7±2.1岁）；52例（38.2%）接受了鼻中隔成形术，84例（61.8%）接受了功能性鼻中隔鼻成形术平均随访时间为3.6±5.1个月。鼻中隔成形术和功能性鼻中隔鼻成形术术后的NOSE评分较术前均有统计学显著下降：鼻中隔成形术前中位数=75，术后中位数=20（z=-5.9，p<0.001）；功能性鼻中隔鼻成形术前中位数=15，术后中位数=7（z=-7.9，p<0.001）。性别、年龄、鼻外伤、既往鼻手术和过敏性鼻炎对两组的NOSE评分变化均无显著影响。手术时的额外手术不是手术类型与NOSE评分之间关系的混杂变量。NOSE量表可靠性分析表明，鼻中隔成形术和功能性鼻中隔鼻成形术患者的内部一致性较高，Cronbach'sα为0.83。
接受鼻中隔成形术或功能性鼻中隔鼻成形术的儿科患者的疾病特异性生活质量有显著改善。性别、鼻外伤、既往鼻手术和过敏性鼻炎对两组的NOSE评分均无显著影响。
