Anderson W D, Wagner N B, Lee K L, White R D, Yuschak J, Behar V S, Selvester R H, Ideker R E, Wagner G S
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.
Am J Cardiol. 1988 Apr 1;61(10):729-33. doi: 10.1016/0002-9149(88)91056-9.
Each of the 54 criteria in the Selvester 32-point QRS scoring system for estimation of myocardial infarct (MI) size has attained greater than or equal to 95% specificity in normal subjects. This study was performed to identify a subset of those criteria with cumulative specificity greater than or equal to 95% and maximal sensitivity for use in screening for the presence of non-acute MI. Coronary angiography and left ventriculography were used to identify 500 normal subjects, 60 patients with isolated anterior MI and 62 patients with isolated inferior MI. Patients with the QRS confounding factors of ventricular hypertrophy, fascicular block or bundle branch block on their electrocardiogram were not included. Using stepwise logistic regression analysis, the screening criteria identified were: (1) Q greater than or equal to 30 ms in aVF, (2) R less than or equal to 10 ms and less than or equal to 0.1 mV in V2 and (3) R greater than or equal to 40 ms in V1. Cumulatively, these 3 screening criteria achieved 84% and 77% sensitivities for inferior and anterior MI groups, respectively. Thus, a set of 3 criteria from the Selvester QRS scoring system is capable of identifying single non-acute anterior or inferior MI in 80% of patients, and falsely indicating presence of MI in only 5% of normal subjects.
用于评估心肌梗死(MI)面积的塞尔维斯特32分QRS评分系统中的54项标准,在正常受试者中每项的特异性均达到或超过95%。本研究旨在从这些标准中识别出一组累积特异性达到或超过95%且具有最大敏感性的标准,用于筛查非急性MI的存在情况。采用冠状动脉造影和左心室造影来确定500名正常受试者、60名孤立性前壁MI患者和62名孤立性下壁MI患者。心电图存在心室肥厚、束支阻滞或分支阻滞等QRS混杂因素的患者未纳入研究。通过逐步逻辑回归分析,确定的筛查标准为:(1)aVF导联Q波大于或等于30毫秒,(2)V2导联R波小于或等于10毫秒且小于或等于0.1毫伏,以及(3)V1导联R波大于或等于40毫秒。这3项筛查标准累积起来,在下壁MI组和前壁MI组中的敏感性分别达到84%和77%。因此,塞尔维斯特QRS评分系统中的一组3项标准能够在80%的患者中识别出单发的非急性前壁或下壁MI,且在仅5%的正常受试者中错误提示存在MI。