IEEE Trans Neural Syst Rehabil Eng. 2021;29:488-496. doi: 10.1109/TNSRE.2021.3057384. Epub 2021 Mar 2.
Spatial navigation is a complex cognitive process based on vestibular, proprioceptive, and visualcues that are integrated and processed by an extensive network of brain areas. The retrosplenial complex (RSC) is an integral part of coordination and translation between spatial reference frames. Previous studies have demonstrated that the RSC is active during a spatial navigation tasks. The specifics of RSC activity under various navigation loads, however, are still not characterized. This study investigated the local information processed by the RSC under various navigation load conditions manipulated by the number of turns in the physical navigation setup. The results showed that the local information processed via the RSC, which was reflected by the segregation network, was higher when the number of turns increased, suggesting that RSC activity is associated with the navigation task load. The present findings shed light on how the brain processes spatial information in a physical navigation task.
空间导航是一种基于前庭、本体感觉和视觉线索的复杂认知过程，这些线索由大脑的广泛网络进行整合和处理。后扣带皮层（RSC）是空间参照系之间协调和转换的重要组成部分。先前的研究表明，RSC 在空间导航任务中是活跃的。然而，在各种导航负荷下，RSC 的活动细节仍未得到明确描述。本研究通过改变物理导航设置中的转弯次数来操纵各种导航负荷条件，研究了 RSC 在不同导航负荷下处理的局部信息。结果表明，通过 RSC 处理的局部信息（由分离网络反映）在转弯次数增加时更高，这表明 RSC 活动与导航任务负荷有关。本研究结果揭示了大脑在物理导航任务中如何处理空间信息。
