Alexander Andrew S, Place Ryan, Starrett Michael J, Chrastil Elizabeth R, Nitz Douglas A
Department of Psychological and Brain Sciences, Boston University, Boston, MA 02215, USA.
Department of Cognitive Science, University of California, San Diego, La Jolla, CA 92093, USA.
Neuron. 2023 Jan 18;111(2):150-175. doi: 10.1016/j.neuron.2022.11.006. Epub 2022 Dec 1.
The last decade has produced exciting new ideas about retrosplenial cortex (RSC) and its role in integrating diverse inputs. Here, we review the diversity in forms of spatial and directional tuning of RSC activity, temporal organization of RSC activity, and features of RSC interconnectivity with other brain structures. We find that RSC anatomy and dynamics are more consistent with roles in multiple sensorimotor and cognitive processes than with any isolated function. However, two more generalized categories of function may best characterize roles for RSC in complex cognitive processes: (1) shifting and relating perspectives for spatial cognition and (2) prediction and error correction for current sensory states with internal representations of the environment. Both functions likely take advantage of RSC's capacity to encode conjunctions among sensory, motor, and spatial mapping information streams. Together, these functions provide the scaffold for intelligent actions, such as navigation, perspective taking, interaction with others, and error detection.
过去十年间，人们对压后皮质（RSC）及其在整合各种输入信息方面的作用产生了令人兴奋的新见解。在此，我们回顾了RSC活动的空间和方向调谐形式的多样性、RSC活动的时间组织以及RSC与其他脑结构的互连特征。我们发现，RSC的解剖结构和动态变化与多种感觉运动和认知过程中的作用更为一致，而不是与任何单一的功能相符。然而，在复杂认知过程中，RSC的作用可能最好用两类更广义的功能来描述：（1）为空间认知转换和关联视角；（2）利用环境的内部表征对当前感觉状态进行预测和错误校正。这两种功能可能都利用了RSC对感觉、运动和空间映射信息流之间结合进行编码的能力。这些功能共同为智能行为提供了框架，如导航、换位思考、与他人互动以及错误检测。
