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饮食干预对成年门诊进食障碍患者的效果:系统评价和证据质量评估。

Dietetic intervention for adult outpatients with an eating disorder: a systematic review and assessment of evidence quality.

机构信息

Boden Collaboration for Obesity, Nutrition, Exercise and Eating Disorders, University of Sydney, Sydney, New South Wales, Australia.

Centre for Trials Research, Cardiff University, Cardiff, Wales.

出版信息

Nutr Rev. 2021 Jul 7;79(8):914-930. doi: 10.1093/nutrit/nuaa105.

Abstract

CONTEXT

Eating disorders (EDs) are complex mental illnesses that require medical, psychological, and dietetic intervention to assist patients achieve recovery.

OBJECTIVE

Available evidence was reviewed regarding dietetic intervention for adult outpatients with an ED and the quality of this evidence was assessed.

DATA SOURCES

Systematic literature searches were conducted using 5 databases (MEDLINE, PreMEDLINE, EMBASE, CINAHL, PsycINFO) for studies comparing adults with an ED receiving a dietetic intervention with those receiving a psychological intervention alone, those receiving a combined dietetic and psychological intervention, or a control group.

DATA EXTRACTION

Literature searches returned 3078 results, with 10 articles reporting on 9 randomized controlled trials meeting the inclusion criteria. The quality of evidence was assessed using the Cochrane Risk-of-Bias tool and Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework.

DATA ANALYSIS

GRADE assessments for studies involving individuals with anorexia nervosa indicated very low quality of evidence for outcomes including weight, ED psychopathology and ED behaviors , and no studies measured nutritional changes. For studies conducted with participants with bulimia nervosa or binge eating disorder, only 1 study included a group receiving combined evidence-based psychological and dietetic intervention. A combined intervention produced moderate-quality evidence for lower attrition, greater abstinence from ED behaviors, and more meals eaten per week in comparison with a stand-alone psychological or dietetic intervention.

CONCLUSIONS

There is currently limited evidence to sufficiently assess the impact of incorporating dietetic interventions into outpatient treatment for adults with an ED; however, available evidence supports clinical practice guidelines that dietetic intervention should not be delivered as a stand-alone treatment. Additional methodologically sound studies in larger samples are required to fully inform dietetic treatment in EDs and incorporation of such interventions as part of a multidisciplinary treatment approach.

摘要

背景

饮食失调(ED)是一种复杂的精神疾病,需要医学、心理和饮食干预来帮助患者康复。

目的

综述了针对 ED 成年门诊患者的饮食干预措施,评估了这些证据的质量。

数据来源

使用 5 个数据库(MEDLINE、PreMEDLINE、EMBASE、CINAHL、PsycINFO)进行系统文献检索,比较了接受饮食干预的 ED 成年患者与仅接受心理干预、联合饮食和心理干预或对照组的患者。

数据提取

文献检索共返回 3078 项结果,其中 10 篇文章报道了符合纳入标准的 9 项随机对照试验。使用 Cochrane 偏倚风险工具和推荐评估、制定与评价(GRADE)框架评估证据质量。

数据分析

涉及神经性厌食症患者的研究的 GRADE 评估表明,体重、ED 精神病理学和 ED 行为等结局的证据质量非常低,并且没有研究测量营养变化。对于针对神经性贪食症或暴食障碍参与者进行的研究,只有 1 项研究纳入了接受基于证据的联合心理和饮食干预的组。与单独的心理或饮食干预相比,联合干预产生了中等质量的证据,表明更低的脱落率、ED 行为的更高戒除率以及每周更多的餐数。

结论

目前,评估将饮食干预纳入 ED 成年门诊治疗的影响的证据有限;但是,现有的证据支持临床实践指南,即饮食干预不应作为单独的治疗方法。需要更多方法严谨的大样本研究来充分告知 ED 中的饮食治疗,并将此类干预措施纳入多学科治疗方法的一部分。

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