Miura K, Shirasawa H
Department of Pathology, Hamamatsu University School of Medicine, Japan.
Am J Clin Pathol. 1988 Apr;89(4):561-4. doi: 10.1093/ajcp/89.4.561.
A primary hepatic tumor with histologic features suggestive of carcinoid tumor is reported, and six previously reported cases reviewed. Tumor cells contained electron dense secretory granules with an average diameter 150-200 nm which demonstrated positive argyrophilic reactions. On immunohistochemistry, chromogranin A was positively stained. No endocrine syndrome was present and an alternative primary source of the tumor was not found, despite an intensive search.