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复方大承气汤鼻饲治疗恶性肠梗阻的疗效。

The effect of compound Da-Cheng-Qi Decoction on the treatment of malignant bowel obstruction with transnasal ileus tube.

机构信息

Department of Nutrition, Tianjin Nankai Hospital, 300100, Tianjin, China.

Department of Gastrointestinal Surgery, Tianjin Nankai Hospital, 300100, Tianjin, China.

出版信息

Complement Ther Clin Pract. 2021 May;43:101316. doi: 10.1016/j.ctcp.2021.101316. Epub 2021 Jan 27.

Abstract

OBJECTIVE

To study the effect of compound Da-Cheng-Qi Decoction (CDCQD) on the treatment of malignant bowel obstruction (MBO) with transnasal ileus tube (TIT).

METHODS

We observed 30 cases of MBO from July 2018 to August 2019. The patients were divided into the control group (n = 15) and the CDCQD group (n = 15) according to a random number table. All patients were inserted the TIT after admission. Twenty-four hours later, the CDCQD group began to take 100 ml CDCQD twice a day for 7 days. The control group took the plain boiled water instead. Other treatment was the same in the two groups. The waistline reduction, the release time of abdominal pain and distention, recovery of exhaust and defecation time, drainage volume of TIT were observed and compared between the two groups.

RESULTS

Three days after insertion of TIT, the abdominal plain film was re-examined in the two groups. Most of the patients' gas-liquid level disappeared and there was no significant difference between the two groups (P > 0.05). The effective rate of CDCQD group (86.7%) was significantly higher than that of control group (53.3%). The recovery time of exhaust and defecation in the CDCQD group was earlier than that in the control group (P < 0.05). The daily drainage volume of TIT in the CDCQD group was less than that in the control group, especially from the fourth day to the sixth day after insertion of TIT, with a significant difference (P < 0.05).

CONCLUSION

TIT is an effective treatment for patients with MBO. With the basis of TIT treatment, CDCQD therapy can improve the curative effect of MBO. It can promote intestinal exhaust and defecation and improves the curative effect of palliative treatment of MBO. It is an effective method to assist Tit in the treatment for MBO patients.

摘要

目的

研究复方大承气汤(CDCQD)对经鼻肠梗阻导管(TIT)治疗恶性肠梗阻(MBO)的影响。

方法

观察 2018 年 7 月至 2019 年 8 月收治的 MBO 患者 30 例,按随机数字表法分为对照组(n=15)和 CDCQD 组(n=15)。所有患者入院后均行 TIT 置管,24 小时后 CDCQD 组开始服用 100 ml CDCQD,每日 2 次,连用 7 天,对照组予等量白开水。两组其他治疗相同。观察并比较两组患者腰围缩小、腹痛腹胀缓解时间、排气排便恢复时间、TIT 引流量。

结果

TIT 置管 3 天后复查两组患者腹部平片,多数患者气液平面消失,两组比较差异无统计学意义(P>0.05)。CDCQD 组有效率(86.7%)明显高于对照组(53.3%)。CDCQD 组排气排便恢复时间早于对照组(P<0.05)。CDCQD 组 TIT 日引流量少于对照组,尤其在 TIT 置管后第 4~6 天,差异有统计学意义(P<0.05)。

结论

TIT 是治疗 MBO 患者的有效方法,在 TIT 治疗基础上联合 CDCQD 治疗可提高 MBO 的疗效,能促进肠道排气排便,提高 MBO 姑息治疗的效果,是辅助 TIT 治疗 MBO 患者的有效方法。

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