Cognitive-perceptual and disorganized schizotypal traits are nonlinearly related to atypical semantic content on tasks of semantic fluency.

Language deficits emerge early in the course of schizophrenia, yet research findings in those at-risk for schizophrenia, such as those with schizotypy, are mixed. The purpose of the present study was to elucidate the relationship of language ability, measured via semantic fluency, to schizotypy, examining both linear and non-linear relations. Semantic fluency data from 295 individuals with varying amounts of schizotypal traits were analyzed utilizing traditional methods (i.e., counting words generated that fit a specific semantic category). The content of semantic fluency responses was also analyzed via a semantic infrequency score (i.e., how infrequent participant responses were relative to all responses generated for the category in the study sample) and a total semantic productivity score (i.e., how many unique words generated overall, including those that did not fit the semantic category). Using traditional methods of scoring, schizotypy was not related to semantic fluency. However, schizotypy was non-linearly related to semantic infrequency and productivity, reflecting atypical semantic activation and processing. In particular, cognitive-perceptual and disorganized, but not interpersonal, traits were related to semantic infrequency and productivity. Valuable content-based information is missed when only analyzing semantic fluency data via the traditional method in the schizophrenia spectrum population. Cognitive-perceptual and disorganized traits, attenuated thought disorder symptoms, evidence the strongest relationship to semantic fluency, further illustrating the link between language and schizophrenia symptoms along the schizophrenia spectrum.