Peng Yun, Guo Xianxian, Liu Junan, Yao Yuanyuan, Guo Hui, Wang Yuan, Xiao Xuan, Ye Lin
Shenzhen Eye Hospital, Shenzhen Key Laboratory of Ophthalmology, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, China.
School of Public Health, Tongji Medical College of Huazhong University of Science Technology, Wuhan, China.
Ann Palliat Med. 2021 Jan;10(1):615-624. doi: 10.21037/apm-20-2526.
To understand the prevalence of diabetic retinopathy (DR) in Shenzhen and to analyze the risk factors for the occurrence and development of DR. Based on the comprehensive information system for diabetes prevention and control in the communities of Shenzhen in 2019, six community health service centers in Shenzhen were used as research sites to carry out multicenter, cross-sectional screening studies.
Cluster random sampling was used to collect data from 904 patients with diabetes in Shenzhen. The occurrence of DR and vision-threatening diabetic retinopathy (VTDR) was analyzed, and multivariate logistic regression was performed to analyze the risk factors for DR and VTDR. EpiData version 3.1 (EpiData Association, Odense, Denmark) statistical software was used to build a database, and Statistical Package for the Social Sciences (SPSS) version 25.0 (IBM Corp., Armonk, N.Y., USA) was used to sort up and analyze the data.
The prevalence of DR among diabetic patients in Shenzhen was 18.58% [95% confidence interval (CI): 16.13-21.3%], and the prevalence of VTDR was 2.43% (95% CI: 1.57-1.2%). The prevalence of DR and VTDR was higher in males than in females. Logistic regression analysis showed that age, disease duration, medication mode, and the occurrence of diabetic peripheral neuropathy (DPN) were associated with the incidence of DR in diabetic patients, and that disease duration, the occurrence of DPN, and diabetic nephropathy were associated with the occurrence of VTDR.
The prevalence of DR in the communities of Shenzhen is high. Age, disease duration, medications, and DPN are the major risk factors for the occurrence of DR.
了解深圳市糖尿病视网膜病变（DR）的患病率，并分析DR发生和发展的危险因素。基于2019年深圳市社区糖尿病防控综合信息系统，选取深圳市6家社区卫生服务中心作为研究地点，开展多中心横断面筛查研究。
采用整群随机抽样方法，收集深圳市904例糖尿病患者的数据。分析DR和威胁视力的糖尿病视网膜病变（VTDR）的发生情况，并进行多因素logistic回归分析，以分析DR和VTDR的危险因素。使用EpiData 3.1版（丹麦欧登塞市EpiData协会）统计软件建立数据库，并用社会科学统计软件包（SPSS）25.0版（美国纽约州阿蒙克市IBM公司）对数据进行整理和分析。
深圳市糖尿病患者中DR的患病率为18.58%[95%置信区间（CI）：16.13 - 21.3%]，VTDR的患病率为2.43%（95%CI：1.57 - 1.2%）。DR和VTDR的患病率男性高于女性。logistic回归分析显示，年龄、病程、用药方式以及糖尿病周围神经病变（DPN）的发生与糖尿病患者DR的发生率相关，病程、DPN的发生以及糖尿病肾病与VTDR的发生相关。
深圳市社区DR患病率较高。年龄、病程、用药情况和DPN是DR发生的主要危险因素。
