Department of general surgery, Chun' an County First People's Hospital, Zhejiang, China.
Medicine (Baltimore). 2021 Jan 22;100(3):e23973. doi: 10.1097/MD.0000000000023973.
: The objective of this study is to explore the influence of the enteral nutrition on primary liver cancer patients after receiving hepatectomy.
: This is a prospective randomized controlled research, which will be conducted between April 2021 and April 2022. Approval is obtained from the Research Ethics Committee of Chun’ an County First People's Hospital (A20201108). Patients who meet the following conditions will be included in this experiment: (1).. the patients aged 18 to 70 years; (2).. in line with clinical diagnostic criteria for primary liver cancer; (3).. planned liver resection for primary liver cancer; (4).. liver function status of Child-Pugh A. Patients with the following characteristics are excluded: (1).. a history of other malignancy; (2).. mental disorder; (3).. severe diabetes or poor glycemic control; (4).. serious complications: bleeding and bile leakage; (5).. poor medical condition: renal failure, respiratory or heart failure. Our investigation includes sixty patients who meet our inclusion criteria. The primary endpoints are length of postoperative hospital stay and liver function index. The secondary results involve the first flatus time and the first defecation time.
: Table 1 indicates the postoperative outcomes between treatment group and control group.
: Enteral nutrition can improve recovery in the primary liver cancer patients after receiving hepatectomy.
: The protocol has been registered in Research Registry (researchregistry6275)
本研究旨在探讨肝切除术后肠内营养对原发性肝癌患者的影响。
这是一项前瞻性随机对照研究，将于 2021 年 4 月至 2022 年 4 月进行。本研究获得淳安县第一人民医院伦理委员会的批准（A20201108）。符合以下条件的患者将纳入本实验：（1）年龄 18-70 岁；（2）符合原发性肝癌的临床诊断标准；（3）原发性肝癌行肝切除术；（4）肝功能状态为 Child-Pugh A。具有以下特征的患者将被排除：（1）其他恶性肿瘤病史；（2）精神障碍；（3）严重糖尿病或血糖控制不佳；（4）严重并发症：出血和胆漏；（5）身体状况不佳：肾衰竭、呼吸或心力衰竭。我们的调查包括 60 名符合纳入标准的患者。主要终点是术后住院时间和肝功能指标。次要结果包括首次肛门排气时间和首次排便时间。
表 1 显示了治疗组和对照组之间的术后结果。
肝切除术后肠内营养可促进原发性肝癌患者的康复。
该方案已在 Research Registry（researchregistry6275）上注册。
