Department of Ultrasound.
Department of Radiology.
Medicine (Baltimore). 2021 Jan 22;100(3):e24243. doi: 10.1097/MD.0000000000024243.
Hepatic splenosis or heterotopic auto-transplantation of spleen in the liver usually occurs after either spleen trauma or surgery. It is of great importance for the differential diagnosis of hepatic splenosis and other liver tumors because surgery is usually not needed if a diagnosis of splenosis is confirmed.
Multiple hepatic masses were revealed by grayscale ultrasound in a 55-year-old man complaining of persistent colic in the upper abdomen after greasy food.
Benign neoplasm with enlarged lymph node in the gastro-hepatic ligament was suspected by contrast enhanced US. The nature of the hepatic mass was undetermined by CECT.
The lesions were surgically removed.
Multiple splenic tissue implants in the liver and peritoneum were confirmed by pathology after surgery. The patient recovered well and was followed up for more than 1 year without recurrence.
Splenosis should be included in the differential diagnosis of focal liver lesion in patients with a history of spleen trauma or surgery. In spite of nonspecific findings on pre-contrast ultrasound, splenosis shows characteristic homogeneous hyperenhancement in arterial and portal phases, as well as prolonged hyperenhancement in the late phase for more than 5 minutes. Furthermore, the confidence of the diagnosis of splenosis may be enhanced by identifying multiple masses with similar enhancing patterns in other regions of the abdominal cavity.
肝脏的脾组织植入或脾的异位自体移植通常发生在脾脏外伤或手术后。对于肝脾组织植入和其他肝脏肿瘤的鉴别诊断非常重要,因为如果确诊为脾组织植入通常不需要手术。
一位 55 岁男性,因进食油腻食物后持续性上腹痛来诊,灰阶超声显示多个肝脏肿块。
增强超声怀疑胃肝韧带内良性肿瘤伴淋巴结肿大,CECT 不能确定肝脏肿块的性质。
手术切除病变。
术后病理证实为多个肝内和腹膜的脾组织植入。患者恢复良好,随访超过 1 年无复发。
对于有脾脏外伤或手术史的患者,局灶性肝脏病变应考虑脾组织植入的鉴别诊断。尽管在超声平扫时无特异性表现,但脾组织植入在动脉期和门静脉期呈特征性均匀强化,且在延迟期强化持续时间超过 5 分钟。此外,在腹腔其他部位发现多个具有相似增强模式的肿块可提高脾组织植入的诊断信心。