Department of Periodontology, School of Dental Medicine, Stony Brook University, Stony Brook, New York, USA.
Private Practice, Forest Hills, New York, USA.
Clin Adv Periodontics. 2022 Jun;12(2):94-100. doi: 10.1002/cap.10149. Epub 2021 Feb 26.
Endodontic-periodontal combined lesions pose a treatment challenge for clinicians, especially when the lesion is persistent and does not show signs of healing after initial endodontic treatment. This case report describes interdisciplinary management of a non-healing combined endodontic-periodontal lesion related to a peri-apical cyst, through a combined approach of apicoectomy and guided tissue regeneration (GTR) with enamel matrix derivative (EMD). Most documented cases have been treated in a sequential manner, with minimal literature present on the effects of a combined approach utilizing EMD for the treatment of these lesions.
A 72-year-old male patient presented with an endodontic-periodontal lesion at tooth #31 initially treated with nonsurgical root canal therapy. The lesion was not responsive to initial endodontic treatment. The patient was informed of questionable prognosis, however wished to save the tooth. Tooth #31 was treated via a combination approach of apicoectomy with bioceramic putty retrograde filling, followed by GTR of the defect using allograft, EMD, and resorbable barrier membrane. The lesion was biopsied and diagnosed as a periapical cyst. Clinical and radiographic examination at 1 year showed resolution of lesion, reduction in probing depths, and good bone fill of the defect.
Traditionally, endodontic-periodontal lesions, which were not responsive to initial therapy, would be given a questionable prognosis and be extracted. This case demonstrates that non-healing, peri-apical lesions may be cystic in nature and effectively managed utilizing a combined approach, with apicoectomy and GTR with EMD, to produce a stable outcome.
当病变持续存在,并且在初始根管治疗后没有显示出愈合迹象时,牙髓-牙周联合病变对临床医生来说是一个治疗挑战。本病例报告描述了通过根尖切除术和引导组织再生(GTR)联合使用釉基质衍生物(EMD)对与根尖周囊肿相关的未愈合联合牙髓-牙周病变的跨学科管理。大多数有记录的病例都是以序贯方式治疗的,很少有文献报道过使用 EMD 联合治疗这些病变的效果。
一名 72 岁男性患者因牙 31 号的牙髓-牙周病变就诊,该病变最初经非手术根管治疗。病变对初始根管治疗无反应。患者被告知预后可疑,但希望保留牙齿。牙 31 号采用根尖切除术联合生物陶瓷腻子逆行填充的联合方法治疗,然后使用同种异体移植物、EMD 和可吸收屏障膜进行缺陷的 GTR。对病变进行了活检,诊断为根尖周囊肿。1 年时的临床和影像学检查显示病变消退,探诊深度减少,缺陷处有良好的骨填充。
传统上,对初始治疗无反应的牙髓-牙周病变预后不佳,需要拔牙。本病例表明,未愈合的根尖周病变可能是囊性的,可以通过根尖切除术和 GTR 联合使用 EMD 来有效治疗,以获得稳定的结果。