Gregg R O
Department of Surgery, Upstate Medical Center, Syracuse, New York.
Am J Surg. 1988 Apr;155(4):540-5. doi: 10.1016/s0002-9610(88)80406-9.
Seven hundred sixty-five patients were operated on in two hospitals in 1979 and 1980, 190 of whom were submitted to operative cholangiography, 41 to primary common duct exploration, and 534 to neither. The incidence of common duct stones was 4 percent in the minimal indications group, 21 percent in the moderate indications group, and 91 percent in the maximal indications group. Follow-up of 5 years revealed 1 recurrence in the minimal group subjected to cholangiography and none among the 534 in whom no cholangiogram was obtained. In the period from 1981 through 1985, eight patients returned with common duct stones, having had no common duct stones at the primary operation. In the same period, 1,722 of 2,533 patients were operated on without cholangiography. The ratio of recurrences to primary operations without cholangiography was 1:225 or 0.45 percent. From these findings, we conclude that on the basis of cost-effectiveness and insurance against subsequent disease and disability, cholangiography is only indicated in patients with moderate indications (minimal jaundice, moderately dilated common duct, pancreatitis, or an increased serum amylase level). Cholangiography is not indicated if there are no indications of obstruction of the common duct by stones (as a routine for small stones in the gallbladder, if the cystic duct is patent, or if there is an isolated increased serum alkaline phosphatase level). Cholangiography is also unnecessary, when the indications of common duct stones are maximal (deep jaundice, huge common duct, cholangitis, or palpable stone). In our geographic area, intraoperative cholangiography should be selected in 7 to 8 percent of patients.
1979年和1980年,两家医院共对765例患者进行了手术,其中190例行术中胆管造影,41例行胆总管一期探查,534例未行上述检查。胆总管结石的发生率在最低指征组为4%,中度指征组为21%,最高指征组为91%。5年随访发现,接受胆管造影的最低指征组中有1例复发,而未行胆管造影的534例患者中无复发。在1981年至1985年期间,8例患者术后出现胆总管结石,其初次手术时并无胆总管结石。同期,2533例患者中有1722例未行胆管造影进行手术。未行胆管造影的初次手术复发率为1:225,即0.45%。基于这些发现,我们得出结论,从成本效益以及预防后续疾病和残疾的角度来看,胆管造影仅适用于中度指征患者(轻度黄疸、胆总管中度扩张、胰腺炎或血清淀粉酶水平升高)。如果没有胆总管结石梗阻的指征(如胆囊小结石、胆囊管通畅或单纯血清碱性磷酸酶水平升高时作为常规检查),则无需进行胆管造影。当胆总管结石指征为最高(深度黄疸、胆总管巨大、胆管炎或可触及结石)时,胆管造影也不必要。在我们所在地区,应选择7%至8%的患者进行术中胆管造影。