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锁骨下动脉-颈外动脉旁路术治疗因颈总动脉和颈内动脉闭塞引起的有症状的严重脑缺血。

Subclavian-external carotid bypass for symptomatic severe cerebral ischemia from common and internal carotid artery occlusion.

作者信息

McGuiness C L, Short D H, Kerstein M D

机构信息

Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana 70112.

出版信息

Am J Surg. 1988 Apr;155(4):546-50. doi: 10.1016/s0002-9610(88)80408-2.

Abstract

Occlusion of the common and internal carotid arteries in a patient with symptomatic severe cerebral ischemia, with or without contralateral carotid disease, portends a poor prognosis. The present study has described our experience with subclavian and external carotid artery revascularization for symptomatic severe cerebral ischemia from common and internal carotid artery occlusion. Nine patients (five men and four women) with a mean age of 62 (range 41 to 82 years) were diagnosed as having symptomatic severe cerebral ischemia. All patients had ipsilateral hemispheric symptoms, seven had amaurosis fugax, and two had associated syncope. Four patients (three men and one woman) were hypertensive, four (two men and two women) had diabetes, eight smoked, and all had a history of coronary artery disease. All of the patients had noninvasive laboratory studies and preoperative angiography, and three had postoperative angiography. Five patients were successfully revascularized to a patent external carotid artery despite nonvisualization by angiography. Six patients had unilateral and three bilateral occlusion of the common and internal carotid arteries appropriate to their symptoms. Using regional anesthesia, four patients underwent a subclavian-external carotid bypass with polytetrafluoroethylene; saphenous vein was used in five; and three had concomitant axilloaxillary bypass grafting with polytetrafluoroethylene. Neurologic improvement (that is, no subsequent deficit and no progression of symptoms) was noted in all nine patients with a follow-up of 4 to 28 months (mean 11.2 months). Two patients died from myocardial infarction 4 and 7 months after operation. Subclavian-external carotid artery bypass is a safe addition to the options for the treatment of symptomatic severe cerebral ischemia with occlusion of the common and internal carotid arteries, visualization of a superior thyroid collateral vessel on the recipient end, and nonvisualization of the external carotid artery.

摘要

在有症状性严重脑缺血的患者中,颈总动脉和颈内动脉闭塞,无论有无对侧颈动脉疾病,预后都很差。本研究描述了我们对锁骨下动脉和颈外动脉血管重建术治疗颈总动脉和颈内动脉闭塞所致症状性严重脑缺血的经验。9例患者(5例男性,4例女性),平均年龄62岁(范围41至82岁),被诊断为有症状性严重脑缺血。所有患者均有同侧半球症状,7例有一过性黑矇,2例伴有晕厥。4例患者(3例男性,1例女性)患有高血压,4例(2例男性,2例女性)患有糖尿病,8例吸烟,且均有冠状动脉疾病史。所有患者均进行了无创实验室检查和术前血管造影,3例进行了术后血管造影。尽管血管造影未显示,但5例患者成功实现了颈外动脉血管重建并保持通畅。6例患者有符合其症状的单侧颈总动脉和颈内动脉闭塞,3例为双侧闭塞。采用区域麻醉,4例患者接受了聚四氟乙烯锁骨下-颈外动脉搭桥术;5例使用了大隐静脉;3例同时进行了聚四氟乙烯腋腋搭桥术。9例患者随访4至28个月(平均11.2个月),均有神经功能改善(即无后续神经功能缺损且症状无进展)。2例患者术后4个月和7个月死于心肌梗死。锁骨下-颈外动脉搭桥术是治疗颈总动脉和颈内动脉闭塞所致症状性严重脑缺血的安全治疗选择之一,前提是受体端甲状腺上侧支血管可显影,而颈外动脉不显影。

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