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颈总动脉闭塞:40例单中心经验

Common Carotid Artery Occlusion: A Single-Center Experience in 40 Cases.

作者信息

Belczak Sergio, Mulatti Grace Carvajal, Abrão Sergio Ricardo, da Silva Erasmo Simão, Aun Ricardo, Puech-Leão Pedro, de Luccia Nelson

机构信息

Department of Vascular Surgery, LIM 2, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil.

Department of Vascular Surgery, Hospital Israelita Albert Einstein, São Paulo, Brazil.

出版信息

Int J Angiol. 2016 Mar;25(1):39-43. doi: 10.1055/s-0035-1547340. Epub 2015 Mar 23.

Abstract

The incidence of common carotid artery occlusion (CCAO) is approximately 3% in patients who undergo angiography for symptomatic cerebrovascular disease; however, few studies have reported on management of this condition. The objective of this article was to analyze risk factors, therapeutic options, and clinical benefits of surgical treatment at a hospital in the city of São Paulo, Brazil. Data were collected from medical records of 40 patients with CCAO who were treated from June 2002 to October 2013. Results were analyzed retrospectively. Most of the patients were men (63.0%), who were significantly younger than women. Most of the participants had hypertension (90.0%), and more than half had a history of smoking (52.5%). The mean number of coexisting comorbidities/risk factors was 2.9 ± 1.0. Half of our sample had ipsilateral patent internal and external carotid artery, and 32.5% presented with an occluded internal carotid artery and a patent external artery. Patients with both an internal and an external occluded carotid artery (12.5%) were significantly older. Contralateral arteriosclerosis was observed in 65% of the patients, mainly represented by 50 to 90% stenosis. Most patients were symptomatic (67.5%), and hemiparesis was the most common symptom (55.0%) found. Most (77.5%) of the patients underwent the medical treatment; one out of three endovascular approaches failed. During the mean follow-up of 55 ± 43 months (range, 2-136 months), 17.5% of the patients died within 4 days after surgical repair and after along 123 months of clinical follow-up. Coexisting comorbidities/risk factors were significantly associated with fatal outcomes, such as acute myocardial infarction. This study provides scientific evidences on treatment and outcomes of CCAO.

摘要

在因有症状的脑血管疾病接受血管造影的患者中,颈总动脉闭塞(CCAO)的发生率约为3%;然而,很少有研究报道这种疾病的治疗方法。本文的目的是分析巴西圣保罗市一家医院手术治疗的危险因素、治疗选择和临床益处。数据收集自2002年6月至2013年10月接受治疗的40例CCAO患者的病历。对结果进行回顾性分析。大多数患者为男性(63.0%),年龄明显小于女性。大多数参与者患有高血压(90.0%),超过一半有吸烟史(52.5%)。并存的合并症/危险因素的平均数量为2.9±1.0。我们样本的一半患者同侧颈内动脉和颈外动脉通畅,32.5%的患者颈内动脉闭塞而颈外动脉通畅。颈内动脉和颈外动脉均闭塞的患者(12.5%)年龄明显较大。65%的患者观察到对侧动脉硬化,主要表现为50%至90%的狭窄。大多数患者有症状(67.5%),偏瘫是最常见的症状(55.0%)。大多数(77.5%)患者接受了药物治疗;三分之一的血管内治疗方法失败。在平均55±43个月(范围为2至136个月)的随访期间,17.5%的患者在手术修复后4天内死亡,经过123个月的临床随访。并存的合并症/危险因素与致命结局显著相关,如急性心肌梗死。本研究为CCAO的治疗和结果提供了科学依据。

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Proximal common carotid artery lesions: endovascular and open repair.近端颈总动脉病变:血管内和开放修复。
Eur J Vasc Endovasc Surg. 2011 Jun;41(6):728-34. doi: 10.1016/j.ejvs.2011.02.024. Epub 2011 Mar 21.

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