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患者报告结果测量信息系统(PROMIS)癌症功能简明三维概况量表的心理测量学特征及效度

Psychometric Characteristics and Validity of the PROMIS Cancer Function Brief 3D Profile.

作者信息

Smith Sean R, Vargo Mary, Zucker David, Shahpar Samman, Gerber Lynn, Henderson Maryanne, Jay Gina, Lee Minji, Cheville Andrea

机构信息

Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, Michigan.

Case Western Reserve University, Cleveland.

出版信息

Arch Phys Med Rehabil. 2022 May;103(5S):S146-S161. doi: 10.1016/j.apmr.2020.12.027. Epub 2021 Feb 4.

DOI:10.1016/j.apmr.2020.12.027
PMID:33548209
Abstract

OBJECTIVE

To develop an item response theory (IRT)-calibrated, patient-reported outcome measure (the PROMIS Cancer Function Brief 3D Profile) of physical function, including associations with fatigue and social participation, in cancer rehabilitation patients.

DESIGN

Large-scale field testing, graded response model IRT analyses, and multivariate regression analysis.

SETTING

Six cancer rehabilitation clinics associated with cancer centers across the United States.

PARTICIPANTS

Adults (N=616) treated in outpatient cancer rehabilitation medicine clinics.

INTERVENTION

Not applicable.

MAIN OUTCOME MEASURES

The PROMIS(r) Cancer Function 3D Profile (including existing items from PROMIS(r) item banks).

RESULTS

A total of 616 patients completed 21 items in the initial item pool. Nine items were removed because of comparatively lower information that they provide according to the IRT item calibrations, low item-total correlations, or bimodal distributions. The remaining items generated a 12-item short form. Regression analyses determined that the items were responsive to and representative of the patient population across trait ranges and multiple domains and subdomains of function.

CONCLUSIONS

This psychometric investigation supports the use of the PROMIS Cancer Function Brief 3D Profile for evaluating function in outpatient cancer rehabilitation patients.

摘要

目的

开发一种经项目反应理论(IRT)校准的、患者报告的身体功能结局测量工具(PROMIS癌症功能简要三维概况),并研究其与癌症康复患者疲劳及社会参与度的相关性。

设计

大规模现场测试、等级反应模型IRT分析和多变量回归分析。

地点

美国六个与癌症中心相关的癌症康复诊所。

参与者

在门诊癌症康复医学诊所接受治疗的成年人(N = 616)。

干预措施

不适用。

主要结局指标

PROMIS(r)癌症功能三维概况(包括PROMIS(r)项目库中的现有项目)。

结果

共有616名患者完成了初始项目库中的21个项目。根据IRT项目校准,9个项目因提供的信息相对较少、项目总分相关性低或双峰分布而被删除。其余项目生成了一个包含12个项目的简短版本。回归分析确定,这些项目在不同特质范围以及功能的多个领域和子领域中对患者群体具有反应性且具有代表性。

结论

这项心理测量学研究支持使用PROMIS癌症功能简要三维概况来评估门诊癌症康复患者的功能。

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