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实施围手术期方案以增强开放式主动脉修复。

Implementation of a perioperative protocol to enhance open aortic repair.

机构信息

Department of Biomedical Sciences, Humanitas University, Milan, Italy.

Vascular Surgery Unit, Humanitas Clinical and Research Center - IRCCS, Milan, Italy.

出版信息

J Vasc Surg. 2021 Aug;74(2):434-441.e2. doi: 10.1016/j.jvs.2020.12.102. Epub 2021 Feb 4.

Abstract

BACKGROUND

Although appreciated for its long-term benefits, open repair of abdominal aortic aneurysms (AAA) is associated with a significant perioperative burden. Enhanced recovery and fast track protocols have improved surgical outcomes in many specialties, but remain scarcely applied in the vascular field.

METHODS

Based on the applied perioperative protocol in a single-center experience, three consecutive study groups were identified among 394 consecutive patients undergoing elective AAA open repair in the last 12 years. Group A included 66 patients who underwent traditional surgery, group B comprised 225 patients treated according to a partially adopted perioperative protocol, and group C consisted of 103 patients, operated in line with a complete perioperative protocol. The aim of this study was to evaluate the impact of the perioperative protocol on recovery time by measuring complication rates, analgesic and antiemetic control, and return of bowel function and ambulation, as well as the length of hospitalization.

RESULTS

The study groups had similar baseline characteristics. A significant improvement was noted in the complication rates (P = .019) and hospitalization time (P < .001) following a complete implementation of the perioperative protocol, where the median hospitalization time was 3 days. No mortality and no readmissions within 30 postoperative days were recorded in this group. There was an improvement in pain levels, as well as postoperative nausea and vomiting control (P < .001).

CONCLUSIONS

Perioperative protocol implementation in AAA open repair is feasible; the clinical outcomes may be improved when strictly adhering to the protocol. All the applied perioperative management interventions seem to have a synergic effect on shortening the recovery time.

摘要

背景

尽管开放性腹主动脉瘤(AAA)修复术具有长期获益,但它与显著的围手术期负担相关。强化康复和快速通道方案已改善了许多专科的手术结果,但在血管领域的应用仍很少。

方法

基于单中心经验中的应用围手术期方案,在过去 12 年中对 394 例择期行开放性 AAA 修复术的连续患者中,确定了 3 个连续的研究组。A 组包括 66 例行传统手术的患者,B 组包括 225 例部分采用围手术期方案治疗的患者,C 组包括 103 例按完整围手术期方案手术的患者。本研究旨在通过测量并发症发生率、镇痛和止吐控制以及肠功能和活动的恢复以及住院时间,评估围手术期方案对恢复时间的影响。

结果

研究组的基线特征相似。完全实施围手术期方案后,并发症发生率(P =.019)和住院时间(P <.001)显著改善,中位住院时间为 3 天。该组无死亡和术后 30 天内再入院。疼痛水平以及术后恶心和呕吐控制得到改善(P <.001)。

结论

在开放性 AAA 修复术中实施围手术期方案是可行的;严格遵循方案可能会改善临床结果。所有应用的围手术期管理干预措施似乎对缩短恢复时间具有协同作用。

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