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影响腹主动脉瘤择期开放修复术中住院时间延长和费用增加的因素:一项病例对照研究

Factors Affecting Longer Stay and Higher Costs during Elective Open Repair for Abdominal Aortic Aneurysm: A Case-Control Study.

作者信息

Shirasu Takuro, Furuya Takatoshi, Nagai Motoki, Nomura Yukihiro

机构信息

Department of Surgery, Asahi General Hospital, Chiba, Japan.

Department of Surgery, Asahi General Hospital, Chiba, Japan.

出版信息

Ann Vasc Surg. 2019 Oct;60:112-119. doi: 10.1016/j.avsg.2019.03.039. Epub 2019 Jun 13.

Abstract

BACKGROUND

Open surgery for abdominal aortic aneurysm (AAA) has the advantage of requiring less reintervention compared with endovascular aneurysm repair. The reduction of the initial hospitalization costs can provide socioeconomic benefits. The objective of this study was to determine the factors associated with an increase in the length of hospital stay and costs of open surgery for AAA.

METHODS

A total of 579 consecutive patients who underwent open surgery for intact AAA and survived, between 1998 and 2015 at Asahi General Hospital in Japan, were included in the analysis. Patients' characteristics, aneurysm morphology, operative procedures, postoperative complications, and postoperative courses were analyzed in relation to the hospital length of stay and costs. Patients with longer stays or higher costs (exceeding the third quartile) were compared with those with stays or costs no more than the third quartile.

RESULTS

The mean patient age was 75 ± 8 years, and 492 patients (85%) were male, with a mean aortic diameter of 57 ± 10 mm. The mean operation time was 214 ± 56 min with an estimated mean blood loss of 444 ± 305 g. Transfusion was required in 28 patients (4.8%) and return to the operating room (RTOR) in 18 patients (3.1%). The median postoperative hospital stay was 7 (7-8) days. Median costs of hospitalization were 12,300 (11,800-13,100) United States Dollar. In the multivariate analysis, the major factors which increased the length of stay were transfusion, late ambulation, and prolonged fasting time. Major risk factors for higher total hospitalization costs were transfusion, RTOR, and longer fasting time.

CONCLUSIONS

Regardless of the patients' comorbidities or aneurysm morphology, avoidance of transfusion and RTOR, combined with early ambulation and enteral feeding in the postoperative care, can reduce the length of stay and total hospitalization costs associated with open surgery for AAA.

摘要

背景

与血管内动脉瘤修复术相比,腹主动脉瘤(AAA)开放手术的优势在于再次干预需求较少。降低初始住院费用可带来社会经济效益。本研究的目的是确定与AAA开放手术住院时间延长和费用增加相关的因素。

方法

纳入1998年至2015年期间在日本朝日综合医院连续接受完整AAA开放手术且存活的579例患者进行分析。分析患者特征、动脉瘤形态、手术操作、术后并发症及术后病程与住院时间和费用的关系。将住院时间较长或费用较高(超过第三四分位数)的患者与住院时间或费用不超过第三四分位数的患者进行比较。

结果

患者平均年龄为75±8岁,492例(85%)为男性,主动脉平均直径为57±10mm。平均手术时间为214±56分钟,估计平均失血量为444±305克。28例患者(4.8%)需要输血,18例患者(3.1%)返回手术室(RTOR)。术后中位住院时间为7(7 - 8)天。住院中位费用为12300(11800 - 13100)美元。多因素分析显示,住院时间延长的主要因素是输血、活动延迟和禁食时间延长。住院总费用较高的主要危险因素是输血、返回手术室和禁食时间延长。

结论

无论患者的合并症或动脉瘤形态如何,避免输血和返回手术室,同时在术后护理中尽早活动和进行肠内喂养,可减少AAA开放手术相关的住院时间和住院总费用。

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