Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Department of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Prev Vet Med. 2021 Mar;188:105278. doi: 10.1016/j.prevetmed.2021.105278. Epub 2021 Jan 27.
Microsporidiosis in pet and stray cats is an emerging zoonotic threat with public health significance worldwide. However, the epidemiological patterns of feline microsporidiosis is still neglected around the world. Hence, current systematic review and meta-analysis aimed at characterizing the prevalence estimates and genotypes of microsporidian parasites among cats of the world. Several databases (PubMed, Web of Science, Scopus, and Google scholar) were systematically explored to find relevant studies. Evaluation of the weighted prevalences among included studies was done using random-effects model. Totally, 30 studies (34 datasets) reported from 19 countries were included in the present work. Microsporidia infection demonstrated higher prevalence rates using microscopy 29.7 % (19.7-42.2 %), followed by serology and molecular techniques with 11 % (4.6-24.2 %) and 8.2 % (5.9-11.4 %), respectively. Moreover, molecular data showed Enterocytozoon bieneusi as the most dominant reported species with 7.4 % (5.1-10.5 %). Also, investigations (11 studies) mostly isolated D genotype among all E. bieneusi genotypes. These results highlight cats as a potential reservoir for acquisition of microsporidia infection in humans, and surveillance programs should be implemented in high-risk areas.
宠物和流浪猫中的微孢子虫病是一种具有全球公共卫生意义的新兴人畜共患病威胁。然而，世界各地仍忽视了猫类微孢子虫病的流行病学模式。因此，目前的系统评价和荟萃分析旨在描述世界范围内猫类微孢子虫寄生虫的流行率估计值和基因型。我们系统地在几个数据库（PubMed、Web of Science、Scopus 和 Google Scholar）中进行了搜索，以找到相关研究。使用随机效应模型对纳入研究的加权流行率进行评估。本研究共纳入来自 19 个国家的 30 项研究（34 个数据集）。使用显微镜检测显示微孢子虫感染的阳性率较高，为 29.7%（19.7%-42.2%），其次是血清学和分子技术，阳性率分别为 11%（4.6%-24.2%）和 8.2%（5.9%-11.4%）。此外，分子数据显示，肠微孢子虫是报告最多的优势物种，阳性率为 7.4%（5.1%-10.5%）。此外，11 项研究主要分离出所有肠微孢子虫基因型中的 D 基因型。这些结果强调了猫作为人类获得微孢子虫感染的潜在储主，应该在高风险地区实施监测计划。
