Suppr超能文献

结直肠癌的鼻咽转移:一例报告

Nasopharyngeal metastasis from colorectal cancer: a case report.

作者信息

Liu Ye-Huan, Lin Bei-Bei, Lv Shi-Xu

机构信息

Department of General Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Department of Thyroid & Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

出版信息

Ann Palliat Med. 2021 Apr;10(4):4911-4816. doi: 10.21037/apm-20-1656. Epub 2021 Jan 26.

Abstract

Metastases from colorectal cancer can occur either through the lymphatic or by hematogenous spread. The most common metastatic sites are the lung and liver. Nasopharyngeal metastasis from colorectal cancer has never been previously reported in the literature on the internet databases we can found. In this paper, we present the case of a 79-year-old male suffering from adenocarcinoma of the rectum with distant metastases to the liver, lung, and nasopharynx. Over the previous 7 years, he had received treatment for rectal cancer including radical surgery (miles surgery), chemotherapy, hepatectomy, and pneumonectomy. After local nasopharyngeal radiotherapy, the patient's quality of life significantly declined and they eventually died of dyspnea caused by airway obstruction due to a nasopharyngeal mass after 7 months of palliative treatment involving pain relief from end-stage disease. Nasopharyngeal metastases from colorectal cancer are extremely rare in the clinic. To the best of our knowledge, this is the first case reporting this occurrence which not only extends the disease database but also warns doctors to pay more attention to these clinical scenarios. Strict monitoring of patients with colorectal cancer after primary treatment could lead to the early diagnosis of metastases and give patients better opportunities for treatment and improved prognosis.

摘要

结直肠癌转移可通过淋巴道或血行播散发生。最常见的转移部位是肺和肝。在我们所能找到的互联网数据库文献中,此前从未有过结直肠癌发生鼻咽转移的报道。在本文中,我们报告了一例79岁男性直肠腺癌患者,其发生了远处转移至肝、肺和鼻咽。在过去7年里,他接受了包括根治性手术(腹会阴联合切除术)、化疗、肝切除术和肺切除术在内的直肠癌治疗。在局部鼻咽放疗后,患者的生活质量显著下降,在接受了7个月的姑息治疗(包括缓解终末期疾病疼痛)后,最终因鼻咽肿物导致气道阻塞引起呼吸困难而死亡。结直肠癌的鼻咽转移在临床上极为罕见。据我们所知,这是首例报道该情况的病例,这不仅扩展了疾病数据库,也提醒医生要更加关注这些临床情况。对结直肠癌患者进行初次治疗后严格监测,可能会早期诊断转移情况,为患者提供更好的治疗机会并改善预后。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验