Bian Yandong, Song Chen, Nie Yuhui, Shen Xin, Hui Fu, Yu Guohua
School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong 261000, P.R. China.
Department of Oncology, Weifang People's Hospital, The First Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong 261000, P.R. China.
Oncol Lett. 2025 May 7;30(1):331. doi: 10.3892/ol.2025.15077. eCollection 2025 Jul.
Breast cancer is a leading cause of cancer-related mortality in women, with metastasis posing a significant clinical challenge. However, spread to the nasopharynx and nasal cavity is exceptionally rare. The current study presents the case of a 53-year-old woman diagnosed with invasive ductal carcinoma of the right breast, which later metastasized to the nasopharynx. Despite undergoing modified radical mastectomy, chemotherapy and endocrine therapy, the patient developed symptoms indicative of distant metastasis. The present study reviews the diagnostic and therapeutic approaches for such rare occurrences, offering insights into effective management. The study analyzes this case alongside previously reported instances with the aim of enhancing awareness and facilitating early detection and intervention.
乳腺癌是女性癌症相关死亡的主要原因，转移带来了重大的临床挑战。然而，扩散至鼻咽部和鼻腔极为罕见。本研究报告了一例53岁女性，诊断为右乳浸润性导管癌，随后转移至鼻咽部。尽管接受了改良根治性乳房切除术、化疗和内分泌治疗，患者仍出现了远处转移的症状。本研究回顾了此类罕见病例的诊断和治疗方法，为有效管理提供见解。该研究将此病例与先前报道的病例进行分析，旨在提高认识并促进早期检测和干预。
