Blackwood J M, Hurd T, Suval W, Machiedo G W
Department of Surgery, UMDNJ, Newark.
Am Surg. 1988 Apr;54(4):212-6.
The reality of late overwhelming post-splenectomy sepsis in adults as well as children has led to more frequent attempts at splenic salvage following splenic trauma. Less attention has been paid to early septic postoperative complications in the splenectomized patient. Associated colon injury has been believed to be a relative contraindication to splenic conservation. If splenectomy enhances the chance of early postoperative infection, then associated colon injury should be an indication for splenic salvage One hundred sixty one patients who had either splenic trauma (58), colon trauma (90), or combined spleen-colon trauma (13) were studied. All patients with splenic trauma had a splenectomy. There was a significantly higher incidence of intra-abdominal sepsis requiring reoperation in the spleen-colon patients (46.7%) than in either of the other groups (spleen = 5.7%, colon = 8.9%, P less than .002 for both comparisons). It is concluded that splenectomy enhances infection in the early postoperative period. When possible, combined spleen-colon trauma should be an indication rather than a contraindication for splenic salvage.
成人及儿童脾切除术后晚期严重败血症的现实情况,已导致在脾外伤后更频繁地尝试保留脾脏。脾切除患者术后早期败血症并发症受到的关注较少。结肠损伤一直被认为是保留脾脏的相对禁忌证。如果脾切除术会增加术后早期感染的几率,那么合并结肠损伤就应成为保留脾脏的指征。对161例患者进行了研究,这些患者分别患有脾外伤(58例)、结肠外伤(90例)或脾-结肠联合外伤(13例)。所有脾外伤患者均接受了脾切除术。脾-结肠联合外伤患者中因腹腔内败血症需要再次手术的发生率(46.7%)显著高于其他两组中的任何一组(脾脏组 = 5.7%,结肠组 = 8.9%,两组比较P均小于0.002)。得出的结论是,脾切除术会增加术后早期的感染几率。在可能的情况下,脾-结肠联合外伤应是保留脾脏的指征而非禁忌证。