Bioengineering Department, Faculty of Engineering, Manisa Celal Bayar University, Muradiye, 45140, Manisa, Turkey.
Protein J. 2021 Jun;40(3):361-366. doi: 10.1007/s10930-021-09966-9. Epub 2021 Feb 7.
Feather is the main waste of poultry industries and constitutes of 90% keratin. Wastes composed of keratin are insoluble and recalcitrant to degradation using conventional decomposing methods. Microbial degradation for keratinous wastes is a promising approach for being eco-friendly and economically. However, due to insolubility of keratinous waste, it has several challenges in upstream and downstream processes such as culture medium optimization, designing of bioreactor, bioreaction/flow type, bioreactor configurations considering mass and heat transfer limitations, rheology derived problems, monitoring of microbial activity, choosing of the right scale-up parameter and purification. In this study, the challenges for keratin degradation processes were discussed with the aim of opening new opportunities for keratinous waste treatments in industrial level.
羽毛是家禽业的主要废弃物，主要由 90%角蛋白组成。由角蛋白组成的废物不溶解，用传统的分解方法很难降解。微生物降解角蛋白废物是一种环保且经济的有前途的方法。然而，由于角蛋白废物的不溶性，它在上游和下游过程中存在着许多挑战，例如培养基优化、生物反应器设计、生物反应/流动类型、考虑到质量和热传递限制的生物反应器配置、流变学衍生问题、微生物活性监测、选择正确的放大参数和净化。本研究讨论了角蛋白降解过程中的挑战，旨在为工业水平上角蛋白废物的处理开辟新的机会。
