• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

个体意外接触工业辐射后的细胞遗传学随访:应用血淋巴细胞双着丝粒频率。

Cytogenetic follow-up of an individual after accidental exposure to industrial radiation using dicentric frequency in blood lymphocytes.

机构信息

Turkish Atomic Energy Authority, Technology Development Department, Yarımburgaz mah. Nükleer araşxtırma yolu, No: 10, 34303 Küçükçekmece, Istanbul, Turkey.

出版信息

Mutat Res Genet Toxicol Environ Mutagen. 2021 Jan-Feb;861-862:503276. doi: 10.1016/j.mrgentox.2020.503276. Epub 2020 Oct 22.

DOI:10.1016/j.mrgentox.2020.503276
PMID:33551095
Abstract

A radiation accident occurred in Bursa, Turkey, in July 2005. An industrial radiographer was exposed to industrial iridium-192 gamma rays for 5 h while laying the natural gas line. After 5 h, the victim had a break because of vomiting and nausea. He ended his work, considering that he might have been exposed to radiation. In a few days, erythema, pain, desquamation, edema started in both hands of the victim. The biological dose assessment was started based on frequencies of dicentrics and rings in peripheral blood lymphocytes ten days after the radiation accident. 6 repeated blood samples were taken for 9 years and analyzed staining after giemsa. After 9 years, decline at dicentric frequencies is significant, but still, dicentric contain cells were detected, which were a strong indicator for external radiation exposure.

摘要

2005 年 7 月,土耳其布尔萨发生了一起辐射事故。一名工业射线照相技师在铺设天然气管道时,5 小时内暴露于工业铱-192γ射线中。5 小时后,由于呕吐和恶心,受害者中断了工作,他认为自己可能受到了辐射。几天后,受害者双手出现红斑、疼痛、脱皮和水肿。辐射事故发生 10 天后,根据外周血淋巴细胞双着丝粒和环的频率开始进行生物剂量评估。在 9 年内,采集了 6 份重复的血样并进行吉姆萨染色分析。9 年后,双着丝粒频率明显下降,但仍检测到含有双着丝粒的细胞,这是外部辐射暴露的有力指标。

相似文献

1
Cytogenetic follow-up of an individual after accidental exposure to industrial radiation using dicentric frequency in blood lymphocytes.个体意外接触工业辐射后的细胞遗传学随访:应用血淋巴细胞双着丝粒频率。
Mutat Res Genet Toxicol Environ Mutagen. 2021 Jan-Feb;861-862:503276. doi: 10.1016/j.mrgentox.2020.503276. Epub 2020 Oct 22.
2
Retrospective cytogenetic analysis of unstable and stable chromosome aberrations in the victims of radiation accident in Bulgaria.保加利亚放射事故受害者不稳定和稳定染色体畸变的回顾性细胞遗传学分析。
Mutat Res Genet Toxicol Environ Mutagen. 2021 Jan-Feb;861-862:503295. doi: 10.1016/j.mrgentox.2020.503295. Epub 2020 Nov 14.
3
Determination of spontaneous dicentric frequencies and establishment of dose-response curves after expose of human peripheral blood lymphocytes to low- and high-dose rate Co gamma rays - the basis for cytogenetic biodosimetry in Vietnam.测定人外周血淋巴细胞在低剂量率和高剂量率钴 γ 射线照射后的自发双着丝粒频率,并建立剂量反应曲线-为越南细胞遗传学生物剂量学奠定基础。
Int J Radiat Biol. 2019 Mar;95(3):307-313. doi: 10.1080/09553002.2019.1549754. Epub 2018 Dec 17.
4
Cytogenetic monitoring of peripheral blood lymphocytes from medical radiation professionals occupationally exposed to low-dose ionizing radiation.职业性低剂量电离辐射接触的医学放射工作人员外周血淋巴细胞染色体监测。
Mutat Res Genet Toxicol Environ Mutagen. 2021 Jul;867:503370. doi: 10.1016/j.mrgentox.2021.503370. Epub 2021 Jun 5.
5
[Rapid dicentric assay of human blood lymphocytes after exposure to low doses of ionizing radiation].[低剂量电离辐射照射后人血淋巴细胞的快速双着丝粒分析]
Radiats Biol Radioecol. 2011 Jul-Aug;51(4):411-8.
6
Biodosimetry for high dose accidental exposures by drug induced premature chromosome condensation (PCC) assay.药物诱导的早熟染色体凝聚(PCC)试验在高剂量意外照射中的生物剂量测定。
Mutat Res. 2010 Jun 17;699(1-2):11-6. doi: 10.1016/j.mrgentox.2010.03.008. Epub 2010 Mar 23.
7
Automatic scoring of dicentric chromosomes as a tool in large scale radiation accidents.自动评分双着丝粒染色体作为大规模辐射事故中的工具。
Mutat Res. 2013 Aug 30;756(1-2):174-83. doi: 10.1016/j.mrgentox.2013.05.013. Epub 2013 May 23.
8
Investigation of new cytogenetic biomarkers specific to high-LET radiation using in vivo and in vitro exposed human lymphocytes.利用体内和体外照射的人淋巴细胞研究高传能线密度辐射特有的新细胞遗传学生物标志物。
Int J Radiat Biol. 2006 Jul;82(7):483-91. doi: 10.1080/09553000600863064.
9
Cytogenetic studies for a group of people living in Japan 1 year after the Fukushima nuclear accident.对福岛核事故发生一年后居住在日本的一群人进行的细胞遗传学研究。
Radiat Prot Dosimetry. 2014 Jun;159(1-4):20-5. doi: 10.1093/rpd/ncu180. Epub 2014 Jun 12.
10
Culture time and reagent minimization in the chemical PCC assay.化学PCC检测中培养时间和试剂用量的最小化
Int J Radiat Biol. 2016 Oct;92(10):558-62. doi: 10.1080/09553002.2016.1206236. Epub 2016 Aug 26.