de Laforcade Louis, Bobot Mickaël, Bellin Marie-France, Clément Olivier, Grangé Steven, Grenier Nicolas, Wynckel Alain, Guerrot Dominique
Service d'endocrinologie-diabétologie-néphrologie, centre hospitalier Pierre-Oudot, 30, avenue du Médipole, 38300 Bourgoin-Jallieu, France; Commission Néphrologie Clinique de la SFNDT, 24, Montée des Roches, Saint-Sorlin, 69440 Chabanière, France.
Commission Néphrologie Clinique de la SFNDT, 24, Montée des Roches, Saint-Sorlin, 69440 Chabanière, France; Centre de néphrologie et transplantation rénale, CHU de conception, 147, boulevard Baille, 13005 Marseille, France; Inserm 1263, Inrae 1260, C2VN, université Aix-Marseille, 27, boulevard Jean-Moulin, 13385 Marseille, France; Comité Scientifique du Club des Jeunes Néphrologues, clinique du Landy, 93400 Saint-Ouen, France.
Nephrol Ther. 2021 Apr;17(2):80-91. doi: 10.1016/j.nephro.2020.10.011. Epub 2021 Feb 5.
Contrast media administration is classically considered to cause or worsen kidney failure. Recent data may moderate this assertion. The European Society of Urogenital Radiology recently published guidelines re-evaluating the precautions before administering contrast media. The present work evaluates the practice of French nephrologists, and provides a commentary on these recommendations based on an updated review of the literature. We conducted survey among French nephrologists, using an electronic questionnaire distributed by the Société Francophone de Néphrologie, Dialyse et Transplantation, the French Intensive care Renal Network and the Club des Jeunes Néphrologues. 266 responses were collected. The European Society of Urogenital Radiology guidelines are poorly known among the panel of nephrologists. Their practices differ from the guidelines by the more frequent and earlier implementation of measures to prevent renal failure post contrast media. In accordance with the guidelines, hydration is prescribed as a first-line preventive measure, mainly with saline and bicarbonate. Inhibitors of the renin-angiotensin-aldosterone system are frequently discontinued before an injection of contrast media, contrary to what is recommended. In conclusion, the European Society of Urogenital Radiology guidelines, which the working group endorses, but which are still too little known and applied in clinical nephrology in France, prompt nephrologists to lift some of the restrictions on the use of PCI as well as on the continuation of ARS inhibitors before injecting PCI.
传统上认为使用造影剂会导致或加重肾衰竭。最近的数据可能会缓和这一论断。欧洲泌尿生殖放射学会最近发布了重新评估使用造影剂前预防措施的指南。本研究评估了法国肾病学家的实践情况,并基于对文献的最新综述对这些建议进行了评论。我们通过法国肾病、透析与移植学会、法国重症监护肾脏网络和青年肾病学家俱乐部分发的电子问卷,对法国肾病学家进行了调查。共收集到266份回复。欧洲泌尿生殖放射学会的指南在肾病学家群体中鲜为人知。他们的做法与指南不同,在造影剂注射后预防肾衰竭的措施实施更为频繁且更早。按照指南,水化被规定为一线预防措施,主要使用生理盐水和碳酸氢盐。与推荐的做法相反,肾素 - 血管紧张素 - 醛固酮系统抑制剂在注射造影剂前经常被停用。总之,工作组认可的欧洲泌尿生殖放射学会指南在法国临床肾病学中仍鲜为人知且应用不足,促使肾病学家放宽一些关于使用经皮冠状动脉介入治疗(PCI)的限制以及在注射PCI前继续使用肾素 - 血管紧张素系统(ARS)抑制剂的限制。