Gedamu Yonas, Taddese Asefa Adimasu, Abdulkadir Mohamed, Hailu Workagegnehu, Abdu Oumer
Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
SAGE Open Med. 2021 Jan 22;9:2050312121989509. doi: 10.1177/2050312121989509. eCollection 2021.
Recently, stroke is becoming the major public health problem in developing countries including Ethiopia. Atrial fibrillation patients are the most vulnerable group for the occurrence of stroke. Knowing the predictors and being aware for it is important for preventing severe complications and death. Therefore, the aim of this study is to assess the prevalence of stroke and identifying significant predictors.
A hospital-based cross-sectional study was performed from 1 December 2018 to 30 September 2019 at University of Gondar Referral Hospital. A total of 242 patients with atrial fibrillation were included in the study. Atrial fibrillation patients were diagnosed by using 12 lead electrocardiographic tracing, in addition to thorough medical history and physical examination and analyzed by the Modular ECG Analysis System (MEANS). We used Epi info 7 and SPSS version 22 software for data entry and analysis purpose, respectively. Both bivariable and multivariable binary logistic regression model were computed to show the relationship of dependent and independent variables.
The prevalence of stroke among atrial fibrillation patients was 19.4% (95% confidence interval (CI): 14.9-25.2). Patients with heart failure (adjusted odds ratio (AOR): 5.70, 95% CI: 2.50-13.24) and thyroid disorder (AOR: 4.98, 95% CI: 1.47-16.85) are at risk of developing stroke.
The prevalence of stroke was higher compared with others studies. Patients with heart failure and thyroid disorders were the risk factor for the development of stroke; therefore, physicians and cardiologists may better to consider all these two disorders when they diagnose stroke in patients with atrial fibrillation.
最近,中风正成为包括埃塞俄比亚在内的发展中国家的主要公共卫生问题。房颤患者是中风发生的最脆弱群体。了解中风的预测因素并对此有所认识对于预防严重并发症和死亡很重要。因此,本研究的目的是评估中风的患病率并确定重要的预测因素。
2018年12月1日至2019年9月30日在贡德尔大学转诊医院进行了一项基于医院的横断面研究。共有242例房颤患者纳入研究。除了详细的病史和体格检查外,房颤患者还通过12导联心电图描记进行诊断,并由模块化心电图分析系统(MEANS)进行分析。我们分别使用Epi info 7和SPSS 22版软件进行数据录入和分析。计算了双变量和多变量二元逻辑回归模型以显示自变量和因变量之间的关系。
房颤患者中风的患病率为19.4%(95%置信区间(CI):14.9 - 25.2)。心力衰竭患者(调整优势比(AOR):5.70,95%CI:2.50 - 13.24)和甲状腺疾病患者(AOR:4.98,95%CI:1.47 - 16.85)有发生中风的风险。
与其他研究相比,中风的患病率更高。心力衰竭和甲状腺疾病患者是中风发生的危险因素;因此,医生和心脏病专家在诊断房颤患者的中风时最好考虑这两种疾病。