Bacharaki Dimitra, Diamandopoulos Athanasios
Department of Nephrology, Attikon University Hospital, Chaidari 12462, Greece.
EKPA, Louros Foundation for the History of Medicine, Chaidari 12462, Greece.
World J Nephrol. 2021 Jan 25;10(1):1-7. doi: 10.5527/wjn.v10.i1.1.
The coronavirus disease-19 (COVID-19) pandemic has been a wake-up call in which has forced us to react worldwide. Health policies and practices have attracted particular attention in terms of human and financial cost. Before COVID-19, chronic kidney disease was already considered a risk multiplier in patients with diabetes and hypertension, the two now being the major risk factors for COVID-19 infection and adverse outcome. In contrast to the urgent need for action, the nephrology field is considered to be in a state of stagnation regarding the management of chronic kidney disease patients who still experience unacceptably high morbidity and mortality. Ironically and paradoxically in a field lacking robust clinical trials, clinical practice is driven by guidelines-based medicine on weak evidence. The Emperor's syndrome, referring to Hans Christian Andersen's fairy tale, has been described in medicine as voluntary blindness to an obvious truth, being a weak evidence-based therapeutic intervention or weak health care. A promising positive example of improving heart and kidney outcomes is the emerging treatment with sodium-glucose cotransporter 2 inhibitors. COVID-19 could boost actions for patient-centered care as a positive shift in nephrology care.
新型冠状病毒肺炎(COVID-19)大流行给我们敲响了警钟,促使全球做出应对。卫生政策和实践在人力和财务成本方面受到了特别关注。在COVID-19之前,慢性肾脏病就已被视为糖尿病和高血压患者的风险倍增因素,而这两种疾病现在是COVID-19感染和不良结局的主要风险因素。与采取行动的迫切需求形成对比的是,在慢性肾脏病患者的管理方面,肾脏病领域被认为处于停滞状态,这些患者的发病率和死亡率仍然高得令人无法接受。具有讽刺意味的是,在一个缺乏有力临床试验的领域,临床实践却由基于证据薄弱的指南医学驱动。“皇帝综合征”,指的是汉斯·克里斯汀·安徒生的童话故事,在医学上被描述为对明显事实的自愿视而不见,即基于薄弱证据的治疗干预或薄弱的医疗保健。改善心脏和肾脏结局的一个有希望的积极例子是新型的钠-葡萄糖协同转运蛋白2抑制剂治疗。COVID-19可能会推动以患者为中心的护理行动,成为肾脏病护理的积极转变。