COVID-19大流行期间妇科癌症手术中的药物预防和个人防护装备（PPE）实践
Pharmacological Prophylaxis and Personal Protective Equipment (PPE) Practices in Gynecological Cancer Surgery During COVID-19 Pandemic.
作者信息
Singh Pooja, Bhandoria Geetu, Maheshwari Amita
机构信息
Division of Gynecologic Oncology, Tata Memorial Centre, Homi Bhabha National Institute, Room no 54, Homi Bhabha Building Tata Memorial Hospital, Parel, Mumbai, 400012 India.
Department of Gynecologic Oncology and Obstetrics, Command Hospital, Kolkata, India.
出版信息
Indian J Gynecol Oncol. 2021;19(1):19. doi: 10.1007/s40944-021-00500-4. Epub 2021 Jan 30.
PURPOSE
In the absence of vaccine, proper use of personal protective equipment (PPE) is the most important strategy to protect healthcare workers against COVID-19 infection. The recommendations on pharmacological prophylaxis against COVID-19 infection are controversial. The aim of current study was to assess PPE practices during surgery on COVID-19 negative gynecological cancer patients and use of pharmacologic prophylaxis by clinicians practicing gynecologic oncology.
METHODS
We disbursed a survey questionnaire through various social media platforms among clinicians practicing gynecologic oncology. The survey consisted of 37 questions divided into five subgroups evaluating demographic details, use of pharmacological prophylaxis against COVID-19, preoperative COVID-19 screening protocol, details on PPE usage and associated discomfort, if any.
RESULTS
Two hundred twenty oncologists from 13 countries responded to the survey. Pharmacological prophylaxis was being used by 85 (38.6%) respondents; most common agent was hydroxychloroquin (HCQ) by 24.5% respondents. Routine preoperative screening for COVID-19 was performed by 214 (97.3%) respondents. Some degree of discomfort during surgery due to PPE use was reported by 170 (77.3%) respondents, which was moderate to severe in 73 (33.2%) respondents. Most common difficulties associated with face mask/shield were problems in communication (69.5%) and breathing (58.1%). Eye protection was associated with poor visibility, fogging and headache. Unusual fatigue attributed to PPE use was experienced by 143(65%) respondents.
CONCLUSION
Use of pharmacological prophylaxis against COVID-19 is controversial and the same is reflected in our survey. Most respondents adhered to PPE use despite experiencing some physical discomfort.
SUPPLEMENTARY INFORMATION
The online version contains supplementary material available at 10.1007/s40944-021-00500-4.
目的
在没有疫苗的情况下，正确使用个人防护装备（PPE）是保护医护人员免受新冠病毒感染的最重要策略。关于新冠病毒感染的药物预防建议存在争议。本研究的目的是评估对新冠病毒检测呈阴性的妇科癌症患者进行手术期间的个人防护装备使用情况，以及妇科肿瘤临床医生使用药物预防的情况。
方法
我们通过各种社交媒体平台向妇科肿瘤临床医生发放了一份调查问卷。该调查由37个问题组成，分为五个子组，评估人口统计学细节、新冠病毒的药物预防使用情况、术前新冠病毒筛查方案、个人防护装备使用细节及相关不适（如有）。
结果
来自13个国家的220名肿瘤学家回复了该调查。85名（38.6%）受访者使用了药物预防；最常用的药物是羟氯喹（HCQ），占24.5%的受访者。214名（97.3%）受访者进行了常规术前新冠病毒筛查。170名（77.3%）受访者报告在手术期间因使用个人防护装备而有一定程度的不适，其中73名（33.2%）受访者的不适为中度至重度。与口罩/面罩相关的最常见困难是沟通问题（69.5%）和呼吸问题（58.1%）。眼部防护与能见度差、起雾和头痛有关。143名（65%）受访者因使用个人防护装备而感到异常疲劳。
结论
新冠病毒的药物预防使用存在争议，这在我们的调查中也有所体现。尽管有一些身体不适，大多数受访者仍坚持使用个人防护装备。
补充信息
在线版本包含可在10.1007/s40944-021-00500-4获取的补充材料。
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