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宫颈癌的危险因素及基层医疗服务提供者在巴氏涂片检查咨询方面的作用:病例对照研究。

Risk factors of cervical cancer and role of primary healthcare providers regarding PAP smears counseling: Case control study.

作者信息

Sadia Halima, Shahwani Irfan Murtaza, Bana Kiran Fatima Mehboob

机构信息

Dr. Halima Sadia, MBBS. Resident, Department of Family Medicine, Ziauddin University, Karachi, Pakistan.

Dr. Irfan Murtaza Shahwani, MBBS. Resident, Department of Family Medicine, Ziauddin University, Karachi, Pakistan.

出版信息

Pak J Med Sci. 2022 Mar-Apr;38(4Part-II):998-1003. doi: 10.12669/pjms.38.4.4969.

Abstract

OBJECTIVES

To determine risk factors of cervical cancer and role of healthcare providers regarding awareness and counseling of PAP-smear.

METHODS

It was case-control study conducted from Jan-2021 till may-2021 at two tertiary care hospitals of Karachi South. The intended sample size was 255 subjects as 105 cases and 150 controls. The inclusion criteria were diagnosed cases of CA Cervix and under the age of 50 years. Controls were recruited from the general population. All the data were entered into SPSS version 23. The odds ratio was calculated to compare the risks of occurring CA cervix among cases and controls. The relationship of risk factors was assessed by binary logistic regression. P-value < 0.05 was considered as statistically significant.

RESULTS

Generally, highly significant p-value (<0.000) was observed; depicted a positive association for a level of education, age at first intercourse, and number of parity in cases of CA cervix and controls (OR=4.3). The correct predicted rate was 68.8% for having CA cervix among controls due to family history, the knowledge of PAP smear screening, ever counseled for a PAP smear, ever tested for a PAP smear, never been tested for PAP smear due to cost.

CONCLUSION

Educational level, age at first intercourse, number of parity was the risk factors of CA cervix. Family history of CA Cervix, knowledge of cervical cancer screening, ever counseled for PAP smear, ever tested for PAP smear, never been tested for PAP smear due to cost were significantly predicted for CA cervix among controls.

摘要

目的

确定宫颈癌的危险因素以及医疗服务提供者在巴氏涂片检查的知晓和咨询方面的作用。

方法

这是一项于2021年1月至2021年5月在卡拉奇南部的两家三级护理医院进行的病例对照研究。预期样本量为255名受试者,其中105例为病例,150例为对照。纳入标准为确诊的宫颈癌病例且年龄在50岁以下。对照从普通人群中招募。所有数据均录入SPSS 23版。计算比值比以比较病例组和对照组中发生宫颈癌的风险。通过二元逻辑回归评估危险因素之间的关系。P值<0.05被认为具有统计学意义。

结果

总体而言,观察到高度显著的P值(<0.000);表明在宫颈癌病例组和对照组中,教育程度、初次性交年龄和产次水平呈正相关(OR = 4.3)。由于家族史、巴氏涂片筛查知识、曾接受过巴氏涂片咨询、曾进行过巴氏涂片检测、因费用从未进行过巴氏涂片检测,对照组中宫颈癌的正确预测率为68.8%。

结论

教育程度、初次性交年龄、产次是宫颈癌的危险因素。在对照组中,宫颈癌家族史、宫颈癌筛查知识、曾接受过巴氏涂片咨询、曾进行过巴氏涂片检测、因费用从未进行过巴氏涂片检测对宫颈癌有显著预测作用。

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