Department of Obstetrics and Gynecology, Perinatology Division, Manisa Celal Bayar University, Manisa, Turkey.
Manisa City Hospital, Manisa, Turkey.
J Perinat Med. 2020 Dec 7;49(4):468-473. doi: 10.1515/jpm-2020-0464. Print 2021 May 26.
Increased placental stiffness is associated with various pathological conditions. Our objective was to evaluate the relation between the second-trimester placental elasticity value in low-risk pregnant women and poor obstetric outcomes.
A total of 143 pregnant women were enrolled. Placental elasticity values were measured using the transabdominal point shear wave elastography method. 10 random measurements were obtained from different areas of the placenta. The mean was accepted as the mean placental elasticity value. Logistic regression analyses were performed to identify independent variables associated with obstetric outcomes.
Second-trimester placental elasticity value was significantly and positively associated with the poor obstetric outcomes (p=0.038). We could predict a poor outcome with 69.2% sensitivity and 60.7% specificity if we defined the placental elasticity cut-off as 3.19 kPa. Furthermore, in the multiple regression model, the placental elasticity value added significantly to the prediction of birth weight (p=0.043).
Our results showed that the pregnancies with a stiffer placenta in the second trimester were associated with an increased likelihood of exhibiting poor obstetric outcomes. Also, placental elasticity was independently associated with birth weight.
胎盘硬度增加与各种病理状况有关。我们的目的是评估低危孕妇中妊娠中期胎盘弹性值与不良产科结局之间的关系。
共纳入 143 名孕妇。使用经腹点剪切波弹性成像法测量胎盘弹性值。从胎盘的不同区域获得 10 个随机测量值。平均值被接受为平均胎盘弹性值。采用逻辑回归分析来确定与产科结局相关的独立变量。
妊娠中期胎盘弹性值与不良产科结局显著正相关（p=0.038）。如果将胎盘弹性的截断值定义为 3.19 kPa，则我们可以以 69.2%的敏感性和 60.7%的特异性预测不良结局。此外，在多元回归模型中，胎盘弹性值对预测出生体重有显著意义（p=0.043）。
我们的结果表明，妊娠中期胎盘较硬的孕妇发生不良产科结局的可能性增加。此外，胎盘弹性与出生体重独立相关。
